14. Iridium-catalyzed Isomerization of Primary Allylic Alcohols Under Mild Reaction Conditions
    Luca Mantilli, Clément Mazet*
    Tetrahedron Lett. 2009, 50, 4141-4144
    [ Supporting Information]

The isomerization of primary allylic alcohols into the corresponding aldehydes has been accomplished using an analogue of Crabtree’s iridium hydrogenation catalyst and by adequately tuning the experimental conditions. A wide range of substrates is converted quantitatively into the desired aldehyde at room temperature in expedient reaction times by using catalyst loading as low as 0.25 mol %.

archive ouverte unige:8418

DOI de la version éditeur : 10.1016/j.tetlet.2009.04.130