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Publication 102
- Picture Perfect: DNA-Templated Photoaffinity Labeling
S. Barluenga, N. Winssinger
ChemBioChem 2013, 14, 1927-1928
Just so far apart and no further: Small molecules target ID by DNA tagging. Nucleic acid hybridization has been used to pair a photo-crosslinking group with a small molecule of interest. Following photoactivation, the protein(s) interacting with the small molecule are covalently linked to a nucleic acid tag.
DOI : 10.1002/cbic.201300416
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