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Publication 31  

  1. Synthesis of a PNA-encoded cysteine protease inhibitor library
    F. Debaene, L. Mejias, J. L. Harris, N. Winssinger
    Tetrahedron 2004, 60, 8677-8690

Peptide nucleic acids (PNAs) have been used to encode a combinatorial library whereby each compound is labeled with a PNA tag which reflects its synthetic history and localizes the compound upon hybridization to an oligonucleotide array. We report herein the full synthetic details for a 4000 member PNA-encoded library targeted towards cysteine protease.

DOI: 10.1016/j.tet.2004.05.107 

open archive unige:24737