31. Modular Asymmetric Synthesis of Pochonin C
    S. Barluenga, P. Lopez, E. Moulin, N. Winssinger
    Angew. Chem. Int. Ed. 2004, 43, 3467-3470

Back to its origins: Pochonin C was synthesized in 11 steps from the four fragments shown in the scheme. This asymmetric synthesis and the conversion of pochonin C into radicicol defines the configuration at the center bearing the chlorine atom as S. Ipc=isopenocampheyl, PG=protecting group.

DOI : 10.1002/anie.200454108 

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