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Publication 61  

  1. DNA-Templated Homo- and Heterodimerization of Peptide Nucleic Acid Encoded Oligosaccharides that Mimick the Carbohydrate Epitope of HIV
    K. Gorska, K.-T. Huang, O. Chaloin, N. Winssinger
    Angew. Chem. Int. Ed. 2009, 48, 7695-7700

All under control: The programmability of hybridization has been utilized to generate a combinatorial library of structures that emulate the topologies of complex carbohydrates interacting with an antibody that shows broad-spectrum activity against HIV. This simple method involves attaching oligosaccharides tagged with peptide nucleic acids onto DNA templates in a controlled manner

DOI: 10.1002/anie.200903328 

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