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Publication 63  

  1. Synthesis of a Resorcylic Acid Lactone (RAL) Library Using Fluorous-Mixture Synthesis and Profile of its Selectivity Against a Panel of Kinases
    R. Jogireddy, P.-Y. Dakas, G. Valot, S. Barluenga, N. Winssinger
    Chem. Eur. J. 2009, 15, 11498-11506

Browsing through the library: A library of cis-enone resorcyclic acids offering important structural activity relationships is reported. Two modifications were found to independently and synergistically improve the activity of this series of compounds, whereas a modification which dramatically simplifies the synthetic accessibility of these compounds was established.

DOI: 10.1002/chem.200901375 

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