Publications

  • Martinent R, Tawffik S, López-Andarias J, Moreau D, Laurent Q, Matile S. (2021) "Dithiolane quartets: thiol-mediated uptake enables cytosolic delivery in deep tissue". Chemical Science. 12(41):13922-9. doi: 10.1039/D1SC04828G.

  • Laurent QMartinent R, Moreau D, Winssinger M, Sakai N, Matile S, (2021) "Oligonucleotide Phosphorothioates Enter Cells by Thiol-Mediated Uptake". Angewandte Chemie. https://doi.org/10.1002/anie.202107327
  • Cheng Y, Pham A-T, Kato T, Lim B, Moreau D, López-Andarias J, et al. (2021) "Inhibitors of thiol-mediated uptake". Chemical Science. doi: 10.1039/D0SC05447J.

  • Jiménez-Rojo N, Leonetti MD, Zoni V, Colom A, Feng S, Iyengar NR, et al. (2020) "Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway. Current Biology". 30(19):3775-87.e7. doi: 10.1016/j.cub.2020.07.059.
  • Bosmani C, Leuba F, Hanna N, Bach F, Burdet F, Pagni M, et al. (2020) "Vacuolins and myosin VII are required for phagocytic uptake and phagosomal membrane recycling in Dictyostelium discoideum". Journal of cell science. 2020;133(13):jcs242974. doi: 10.1242/jcs.242974.
  • Martinent R., López-Andarias J., Moreau D., Cheng Y, Sakai N., Matile S. (2020). "Automated high-content imaging for cellular uptake, from the Schmuck cation to the latest cyclic oligochalcogenides". Beilstein Journal of Organic Chemistry 16, 2007–2016. doi:10.3762/bjoc.16.167
  • Mercier V., Larios J., Molinard G., Goujon A., Matile S., Gruenberg J., Roux A. (2020). "Endosomal membrane tension regulates ESCRT-III-dependent intra-lumenal vesicle formation". Nature Cell Bioliology. doi: 10.1038/s41556-020-0546-4
  • López-Andarias J., Saarbach J., Moreau D., Cheng Y., Derivery E., Laurent Q., González-Gaitán M., Winssinger N., Sakai N., Matile S. (2020). "Cell-Penetrating Streptavidin: A General Tool for Bifunctional Delivery With Spatiotemporal Control, Mediated by Transport Systems Such as Adaptive Benzopolysulfane Networks". Journal of the American. Chemical Society. DOI: 10.1021/jacs.9b13621
  • Larios J., Mercier V., Roux A., Gruenberg J. "ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes", Journal of Cell Biology. 2020. March 2.
  • Moreau D., Vacca F., Vossio S., Scott C., Colaco A., Paz Montoya J., Ferguson C., Damme M., Moniatte M., Parton R.G., Platt F.M., Gruenberg J., “Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice”, EMBO Rep., 2019 May 22.
  • Vacca F., Vossio S., Mercier V., Moreau D., Johnson S., Scott C.C., Paz Montoya J., Moniatte M., Gruenberg J., “Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells“, J. Lipid Res., pii: jlr.M089979, doi: 10.1194/jlr.M089979, 2019.
  • Banach-Orłowska M., Jastrzębski K., Cendrowski J., Maksymowicz M., Wojciechowska K., Korostyński M., Moreau D., Gruenberg J., Miaczynska M., “The topology of lymphotoxin &[beta] receptor (LT&[beta]R) accumulated upon endolysosomal dysfunction dictates the NF-&[kappa]B signaling outcome“, Journal of Cell Science, 2018.
  • Eren R. O., Kopelyanskiy D., Moreau D., Chapalay J. B., Chambon M., Turcatti G., Lye L.-F., Beverley S. M., Fasel N., “Development of a semi-automated image-based high-throughput drug screening system“, Frontiers in bioscience (Elite edition), 10, 242-253, 2018.
  • Moreau D., Gruenberg J., “Automated Microscopy and High Content Screens (Phenotypic Screens) in Academia Labs“, Chimia, Vol. 70, Number 12, December 2016, pp. 878-882(5).
  • Wu K.X., Phuektes P., Kumar P., Yen Lin Goh G., Moreau D., Tak Kwong Chow V., Bard F., Jang Hann Chu J., “Human genome-wide RNAi screen reveals host factors required for enterovirus 71 replication“, Nature Communications, 2016.
  • Wong H.H., Kumar P., Tay F.P., Moreau D., Liu D.X., Bard F., “Genome-wide screen reveals VCP requirement for coronavirus exit from endosomes“, Journal of Virology, 2015, 89(21):11116-28.
  • Kumar P., Goh G., Wongphayak S., Moreau D., Bard F., “ScreenSifter: analysis and visualization of RNAi screening data“, BMC Bioinformatics, 2013, 14(1):290.
  • Moreau D., Bard F., “Comprendre et combattre les toxines A/B en décryptant leur transport intracellulaire“, Medecine/sciences, 2012, 28, 1, 28-31.
  • Moreau D., Scott C., Gruenberg J., “A Novel Strategy to Identify Drugs that Interfere with Endosomal Lipids“, CHIMIA International Journal for Chemistry, 2011, 65, 846-848.
  • Moreau D., Kumar P., Wang S.C., Chaumet A., Chew S.Y., Chevalley H., Bard F., “Genome-wide RNAi screens identify genes required for Ricin and PE intoxications“, Developmental Cell, 2011, 21, 2, 231-244.
  • Chia N.Y., Chan Y.S., Feng B., Lu X., Orlov Y.L., Moreau D., Kumar P., Jiang J., Soh B.S., Huss M., Kraus P., Lufkin T., Lim B., Clarke N., Bard F., Ng. H.H., “A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity“, Nature, 2010, 468, 316-320.