BEAM Platform (Biophysics, Engineering and Analysis of Macromolecules) is a pilot platform offered by the Barabas group at the MOCEL department to provide services for molecular characterization of proteins, nucleic acids and their ligands to research groups at the University of Geneva. BEAM brings together services across biophysics measurement, X-ray crystallography structure determination, data analysis and molecular modelling to support researchers in their projects across diverse fundamental and biomedical topics.
Specifics about the available technologies can be found on Technologies & Services tab and include:
- Differential Scanning Fluorimetry (nanoDSF)
- Microscale Thermophoresis (MST)
- Mass Photometry
- Surface Plasmon Resonance (SPR)
- Size-Exclusion Chromatography with Multi-Angle Light Scattering (SEC-MALS)
- Crystallography
- Protein Structure Prediction & Analysis
- AI/Structure-guided Protein Engineering
- Molecular Dynamics Simulations
- Hydrogen Deuterium Exchange Mass Spectrometry (HDX-MS) and Cross-linking Mass Spectrometry (XL-MS) Data Analysis
- AlphaScreen
- Fluorescence Anisotropy Spectroscopy