Scientific Publications and Book Chapters

The top 3 articles for lentivector design, production and use.


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The full list:

(2020) Constanthin PE, Contestabile A, Petrenko V, Quairiaux C, Salmon P, Hüppi PS, Kiss JZ.

Endogenous erythropoietin signaling regulates migration and laminar positioning of upper-layer neurons in the developing neocortex.

Development, Oct 7;147(19):dev190249


(2020) Andreoli E, Petrenko V, Constanthin PE, Contestabile A, Bocchi R, Egervari K, Quairiaux C, Salmon P, Kiss JK.

Transplanted Embryonic Neurons Improve Functional Recovery by Increasing Activity in Injured Cortical Circuits.

Cereb Cortex, Jun 30;30(8):4708-4725.


(2019) Viale B, Song L, Petrenko V, Wenger Combremont AL, Contestabile A, Bocchi R, Salmon P, Carleton A, An L, Vutskits L, Kiss JZ

Transient Deregulation of Canonical Wnt Signaling in Developing Pyramidal Neurons Leads to Dendritic Defects and Impaired Behavior.

Cell Rep, Apr 30;27(5):1487-1502.


(2019) Rousset F, Salmon P, Bredl S, Cherpin O, Coelho M, Myburgh R, Alessandrini M, Perny M, Roccio M, Speck RF, Senn P, Krause KH.

Optimizing Synthetic miRNA Minigene Architecture for Efficient miRNA Hairpin Concatenation and Multi-target Gene Knockdown.

Mol Ther Nucleic Acids, Mar 1;14:351-363.


(2017) Bocchi R, Egervari K, Carol-Perdiguer L, Viale B, Quairiaux C, De Roo M, Boitard M, Oskouie S, Salmon P, Kiss JZ.

Perturbed Wnt signaling leads to neuronal migration delay, altered interhemispheric connections and impaired social behavior.

Nat Commun. Oct 27;8(1):1158.


(2017) Kanemitsu M, Tsupykov O, Potter G, Boitard M, Salmon P, Zgraggen E, Gascon E, Skibo G, Dayer AG, Kiss JZ.

EMMPRIN overexpression in SVZ neural progenitor cells increases their migration towards ischemic cortex.

Exp Neurol. Nov;297:14-24.


(2017) Petrenko V, van de Looij Y, Mihhailova J, Salmon P, Hüppi PS, Sizonenko SV, Kiss JZ.

Multimodal MRI Imaging of Apoptosis-Triggered Microstructural Alterations in the Postnatal Cerebral Cortex.

Cereb Cortex. Feb 3:1-14.


(2016) Tieng V, Cherpin O, Gutzwiller E, Zambon AC, Delgado C, Salmon P, Dubois-Dauphin M, Krause KH.

Elimination of proliferating cells from CNS grafts using a Ki67 promoter-driven thymidine kinase.

Mol Ther Methods Clin Dev., 6, 16069.


(2016) Egervari K, Potter G, Guzman-Hernandez ML, Salmon P, Soto-Ribeiro M, Kastberger B, Balla T, Wehrle-Haller B, Kiss JZ.

Astrocytes spatially restrict VEGF signaling by polarized secretion and incorporation of VEGF into the actively assembling extracellular matrix.

Glia, 64, 440-56.


(2015) Petrenko V, Mihhailova J, Salmon P, Kiss JZ.

Apoptotic neurons induce proliferative responses of progenitor cells in the postnatal neocortex.

Exp Neurol. 273, 126-137.


(2015) Myburgh R, Ivic S, Pepper MS, Gers-Huber G, Li D, Audigé A, Rochat MA, Jaquet V, Regenass S, Manz MG, Salmon P, Krause KH, Speck RF.

Lentivector knock-down of CCR5 in hematopoietic stem cells confers functional and persistent HIV-1 resistance in humanized mice.

J Virol. Jul;89 (13):6761-72. (PDF)


(2015) Boitard M, Bocchi R, Egervari K, Petrenko V, Viale B, Gremaud S, Oskouie S, Zgraggen E, Salmon P and Kiss JK.

Wnt signaling regulates multipolar to bipolar transition of migrating neurons in the cerebral cortex.

Cell Reports. 10, 1349-61.


(2014) Myburgh R, Cherpin O, Schlaepfer E, Rehrauer H, Speck RF, Krause KH, Salmon P.

Optimization of critical hairpin features allows miRNA-based gene knock-down upon single-copy transduction.

Molecular Therapy Nucleic Acids, 3, e207 (PDF)


(2013) Rady B, Chen Y, Vaca P, Wang Q, Wang Y, Salmon P, Oberholzer J.

Overexpression of E2F3 promotes proliferation of functional human β cells without induction of apoptosis.

Cell Cycle. 12, 2691–2702. (PDF)


(2013) Salmon P.

Generation of human cell lines using lentiviral-mediated genetic engineering.

Methods in Molecular Biology. 945, 417-48. (PDF)


(2012) Pulimeno P, Mannic T, Sage D, Giovannoni L, Salmon P, Lemeille S, Giry-Laterriere M, Unser M, Bosco D, Bauer C, Morf J, Halban P, Philippe J, Dibner C.  

Autonomous and self-sustained circadian oscillators displayed in human islet cells.

Diabetologia. 56, 497-507.


(2012) Zgraggen E,  Boitard M, Roman I, Kanemitsu M, Potter G, Salmon P, Vutskits L, Dayer AG, Kiss JZ.

Early postnatal migration and development of layer II pyramidal neurons in the rodent cingulate/retrosplenial cortex.

Cereb Cortex. 22, 144-57.


(2011) Giry-Laterriere M, Cherpin O, Kim YS, Jensen J, Salmon P.

Polyswitch Lentivectors: "All-in-one" lentiviral vectors for drug-inducible gene expression, live selection and recombination cloning.

Hum Gene Ther. 22, 1255-67. (PDF)


(2011) Giry-Laterriere M, Verhoeyen E, Salmon P.

Lentiviral Vectors.

Methods in Molecular Biology. 737, 183-209. (PDF)


(2010) Barde I, Salmon P, Trono D. Production and titration of lentiviral vectors. Curr Protoc Neurosci. Chapter 4:Unit 4.21.


(2010) Sage D, Unser M, Salmon P, Dibner C.

A software solution for recording circadian oscillator features in time-lapse live cell microscopy.

Cell Div. 5,17-31.


(2009) Unger C, Gao S, Cohen M, Jaconi M, Bergstrom R, Holm F, Galan A, Sanchez E, Irion O, Dubuisson JB , Giry-Laterriere M, Salmon P, Simon C, Hovatta O, Feki A.

Immortalized human skin fibroblast feeder cells support growth and maintenance of both human embryonic and induced pluripotent stem cells.

Hum Reprod. 24, 2567-81 (PDF)


(2009) Jenny B, Kanemitsu M, Tsupykov O, Potter G, Salmon P, Zgraggen E, Gascon E, Skibo G, Dayer AG, Kiss JZ.

Fibroblast growth factor-2 overexpression in transplanted neural progenitors promotes perivascular cluster formation with a neurogenic potential.

Stem Cells. 27, 1309-17.


(2009) Fulcher ML, Gabriel SE, Olsen JC, Tatreau JR, Gentzsch M, Livanos E, Saavedra MT, Salmon P, Randell SH.

Novel human bronchial epithelial cell lines for cystic fibrosis research.

Am J Physiol Lung Cell Mol Physiol. 296, L82-91 (PDF)


(2007) Dayer AG, Jenny B, Sauvain MO, Potter G, Salmon P, Zgraggen E, Kanemitsu M, Gascon E, Sizonenko S, Trono D, Kiss JZ.

Expression of FGF-2 in neural progenitor cells enhances their potential for cellular brain repair in the rodent cortex.

Brain. 130, 2962-76


(2007) Salmon P and Trono D.

Production and Titration of Lentiviral Vectors.

In "Current Protocols in Human Genetics " (JL Haines, BR Korf, CC Morton, CE Seidman, JG Seidman, and DR Smith, eds.) Suppl. 53 , pp. 12.10.1-12.10.24. John Wiley & Sons, Hoboken, NJ.


(2007) Fodor A, Harel C, Fodor L, Armoni M, Salmon P, Trono D, Karnieli E.

Adult rat liver cells transdifferentiated with lentiviral IPF1 vectors reverse diabetes in mice: an ex vivo gene therapy approach.

Diabetologia.50, 121-130.


(2006) Salmon P and Trono D.

Production and Titration of Lentiviral Vectors.

In "Current Protocols in Neuroscience" (JN Crawley, CR Gerfen, MA Rogawski, DR Sibley, P Skolnick, and S Wray, eds.) Suppl. 37, pp. 4.21.1-4.21.23. John Wiley & Sons, Hoboken, NJ.


(2006) Vutskits GV, Salmon P, Mayor L, Vutskits L, Cudre-Mauroux C, Soriano J, Montesano R, Maillet P, Sappino AP.

A role for atm in E-cadherin-mediated contact inhibition in epithelial cells.

Breast Cancer Res Treat.99, 143-53


(2006) Eberhardt M, Salmon P, von Mach MA, Hengstler JG, Brulport M, Linscheid P, Seboek D, Oberholzer J, Barbero A, Martin I, Muller B, Trono D, Zulewski H.

Multipotential nestin and Isl-1 positive mesenchymal stem cells isolated from human pancreatic islets.

Biochem Biophys Res Commun.345, 1167-76


(2005) Salmon P and Trono D.

Design and Production of HIV-derived vectors.

In "Cell Biology: A Laboratory Handbook", 3rd Edition, Elsevier, San Diego


(2005) Kvell K, Nguyen TH, Salmon P, Glauser F, Werner-Favre C, Barnet M, Schneider P, Trono D, Zubler RH. Transduction of CpG DNA-stimulated primary human B cells with bicistronic lentivectors. Molecular Therapy. 12, 892-9


(2005) Nguyen TH, Mai G, Villiger P, Oberholzer J, Salmon P, Morel P, Buhler L, Trono D.

Treatment of acetaminophen-induced acute liver failure in the mouse with conditionally immortalized human hepatocytes.

Journal Hepatology. 43, 1031-37


(2004) Bobardt MD, Salmon P, Wang L, Esko JD, Gabuzda D, Fiala M, Trono D, Van der Schueren B, David G, Gallay PA.

Contribution of proteoglycans to human immunodeficiency virus type 1 brain invasion.

Journal of Virology, 78, 6567-84


(2003) Cudre-Mauroux C, Occhiodoro T, Konig S, Salmon P, Bernheim L, Trono D.

Lentivector-mediated transfer of Bmi-1 and telomerase in muscle satellite cells yields a duchenne myoblast cell line with long-term genotypic and phenotypic stability.

Hum Gene Ther. 14, 1525-33


(2003) Ritz-Laser B, Gauthier BR, Estreicher A, Mamin A, Brun T, Ris F, Salmon P, Halban PA, Trono D, Philippe J.

Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription.

Diabetologia, 46, 810-21


(2003) Kostic C, Chiodini F, Salmon P, Wiznerowicz M, Deglon N, Hornfeld D, Trono D, Aebischer P, Schorderet DF, Munier FL, Arsenijevic Y.

Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina.

Gene Ther., 10, 818-21


(2003) Bovia F, Salmon P, Matthes T, Kvell K, Nguyen TH, Werner-Favre C, Barnet M, Nagy M, Leuba F, Arrighi JF, Piguet V, Trono D, Zubler RH.

Efficient transduction of normal human B lymphocytes and non-dividing myeloma B cells with HIV-1-derived lentiviral vectors.

Blood, 101, 1727-33


(2003) Woods NB, Muessig A, Schmidt M, Flygare J, Olsson K, Salmon P,Trono D, Von Kalle C, Karlsson S.

Lentiviral vector transduction of NOD/SCID repopulating cells results in multiple vector integrations per transduced cell: risk of insertional mutagenesis.

Blood, 101,1284-9


(2002) Sandrin V, Boson B, Salmon P, Gay W, Negre D, Le Grand R, Trono D and Cosset FL.

Lentiviral vectors pseudotyped with a modified RD114 envelope glycoprotein show increased stability in sera and augmented transduction of primary lymphocytes and CD34+ cells derived from human and nonhuman primates.

Blood, 100, 823-32


(2002) Maurice M, Verhoeyen E, Salmon P, Trono D, Russell SJ and Cosset FL.

Efficient gene transfer into human primary blood lymphocytes by surface-engineered lentiviral vectors that display a T cell-activating polypeptide.

Blood, 99, 2342-50


(2002) Salmon P and Trono D.

Lentiviral vectors for the gene therapy of lympho-hematological disorders.

Curr Top Microbiol Immunol. 261, 211-27


(2001) Salmon P, Arrighi J-F, Piguet V, Chapuis B, Zubler RH, Trono D and Kindler V.

Transduction of CD34+ cells with lentiviral vectors enables the production of large quantities of transgene-expressing immature and mature dendritic cells.

Journal of Gene Medicine, 3, 311-320 (PDF)


(2000) Salmon P, Kindler V, Ducrey O, Chapuis B, Zubler RH and Trono D.

High-level transgene expression in human hematopoietic progenitors and differentiated blood lineages after transduction with improved lentiviral vectors.

Blood, 96, 3392-3398 (PDF)


(2000) Salmon P, Oberholzer J, Occhiodoro T, Morel P, Lou J and Trono D.

Reversible Immortalization of Human Primary Cells by Lentivector-Mediated Transfer of Specific Genes.

Molecular Therapy, 2, 404-414 (PDF