Publications
- “Synthetic Peroxides as Potent Antimalarials. News and Views”
Jefford, C.W.
Curr. Top. Med. Chem. (Sharjah, United Arab Emirates) 2012, 12, 373-399.
- “Unusually stable abnormal karyotype in a highly aggressive melanoma negative for telomerase activity”
Gagos, S.; Papaioannou, G.; Chiourea, M.; Merk-Loretti, S.; Jefford, C.-E.; Mikou, P.; Irminger-Finger, I.; Liossi, A.; Blouin, J.-L.; Dahoun, S.
Mol. Cytogenet. 2008, 1, 20.
- “New developments in synthetic peroxidic drugs as artemisinin mimics”
Jefford, C.W.
Drug Discov. Today 2007, 12, 487-495.
- “Blood schizontocidal activity of selected 1,2,4-trioxanes (Fenozans) against the multidrug-resistant strain of Plasmodium yoelii nigeriensis (MDR) in vivo”
Tripathi, R.; Jefford, C.W.; Dutta, G.P.
Parasitology 2006, 133, 1-9.
- “Synthetic peroxides as antimalarials”
Jefford, C.W.
Curr. Opin. Investig. Drugs 2004, 5, 866-872.
- “Photochemical Study of [33](1,3,5)Cyclophane and Emission Spectral Properties of [3n]Cyclophanes (n = 2-6)”
Nogita, R.; Matohara, K.; Yamaji, M.; Oda, T.; Sakamoto, Y.; Kumagai, T.; Lim, C.; Yasutake, M.; Shimo, T.; Jefford, C.W.; Shinmyozu, T.
J. Am. Chem. Soc. 2004, 126, 13732-13741.
- “A Concise Synthesis of Siphonodictidine”
Jefford, C.W.; Rossier, J.-C.; Boukouvalas, J.; Sledeski, A.W.; Huang, P.-Z.
J. Nat. Prod. 2004, 67, 1383-1386.
- “PREFACE [Hot Topic: Heterocyclic Chemistry (Guest Editor: Charles W. Jefford)]”
Jefford, C.W.
Curr. Org. Chem. 2003, 7, i.
- “A kinetic and mechanistic study on the thermal decomposition reactions of cis- and trans-fused 1,2,4-trioxanes”
Cafferata, L.F.R.; Jeandupeux, R.; Romanelli, G.P.; Mateo, C.M.; Jefford, C.W.
Afinidad 2003, 60, 206-211.
- “Kinetics and mechanism of thermolysis of fluorine-substituted 1,2,4-trioxanes in n-hexane solution”
Cafferata, L.F.R.; Jefford, C.W.; Rimada, R.S.
Afinidad 2002, 59, 670-675.
- “The chemotherapy of rodent malaria. LX. The importance of formulation in evaluating the blood schizontocidal activity of some endoperoxide antimalarials.”
Peters, W.; Fleck, S.L.; Robinson, B.L.; Stewart, L.B.; Jefford, C.W.
Ann. Trop. Med. Parasitol. 2002, 96, 559-573.
- “Why Artemisinin and Certain Synthetic Peroxides are Potent Antimalarials. Implications for the Mode of Action”
Jefford, C.W.
Curr. Med. Chem. 2001, 8, 1803-1826.
- “Solvent and Substituent Effects on the Kinetics of Thermolysis of cis-Fused 1,2,4-Trioxanes”
Cafferata, L.F.R.; Jefford, C.W.
Molecules 2001, 6, 699-709.
- “Preface”
Jefford, C.W.
Curr. Org. Chem. 2001, 5, i.
- “New Bromoterpenes from the Red Alga Laurencia luzonensis”
Kuniyoshi, M.; Marma, M.S.; Higa, T.; Bernardinelli, G.; Jefford, C.W.
J. Nat. Prod. 2001, 64, 696-700.
- “Kinetics and mechanism of thermolysis of fluorine substituted 1,2,4-trioxanes in methanol solution”
Cafferata, L.F.R.; Jefford, C.W.; Rimada, R.S.
Int. J. Chem. Kinet. 2000, 32, 523-528.
- “3-Bromobarekoxide, an unusual diterpene from Laurencia luzonensis”
Kuniyoshi, M.; Marma, M.S.; Higa, T.; Bernardinelli, G.; Jefford, C.W.
Chem. Commun. 2000, 1155-1156.
- “Epiartemisinin, a Remarkably Poor Antimalarial: Implications for the Mode of Action”
Jefford, C.W.; Burger, U.; Millasson-Schmidt, P.; Bernardinelli, G.; Robinson, B.L.; Peters, W.
Helv. Chim. Acta 2000, 83, 1239-1246.
- “The Structure and Antimalarial Activity of Some 1,2,4-Trioxanes, 1,2,4,5-Tetroxanes, an Bicyclic Endoperoxides. Implications for the Mode of Action”
Jefford, C.W.; Rossier, J.-C.; Milhous, W.K.
Heterocycles 2000, 52, 1345-1352.
- “Pyrroles as Building Blocks for the Enantioselective Synthesis of Indolizidines”
Jefford, C.W.
Curr. Org. Chem. 2000, 4, 205-230.
- “Preface”
Jefford, C.W.
Curr. Org. Chem. 2000, 4, i.
- “Correlating the Molecular Electrostatic Potentials of Some Organic Peroxides with Their Antimalarial Activities”
Jefford, C.W.; Grigorov, M.; Weber, J.; Lüthi, H.P.; Tronchet, J.M.J.
J. Chem. Inf. Comput. Sci. 2000, 40, 354-357.
- “Stereoselective Oxidative Dimerization of (1R)-Camphor. A Short Synthesis of exo,exo′-3,3′-Biisoborneol”
McNulty, J.; Millar, M.J.; Bernardinelli, G.; Jefford, C.W.
J. Org. Chem. 1999, 64, 5312-5314.
- “The Efficient Synthesis of 1,2-Dioxetanes from Indene and 1,2-Dihydronaphthalene”
Jefford, C.W.; Deheza, M.F.
Heterocycles 1999, 50, 1025-1031.
- “The Structure and Antimalarial Activity of Some cis-Fused Bicyclic 1,2,4-Trioxane Derivatives”
Jefford, C.W.; Jaggi, D.; Kohmoto, S.; Timári, G.; Bernardinelli, G.; Canfield, C.J.; Milhous, W.K.
Heterocycles 1998, 49, 375-383.
- “Highly Diastereoselective Conjugate Addition of Lithiated γ-Crotonolactone (But-2-en-4-olide) to Cyclic Enones To Give Syn-Adducts: Application to a Brefeldin Synthesis”
Haynes, R.K.; Lam, W.W.-L.; Yeung, L.-L.; Williams, I.D.; Ridley, A.C.; Starling, S.M.; Vonwiller, S.C.; Hambley, T.W.; Jefford, C.W.; Lelandais, P.
J. Org. Chem. 1998, 63, 5294.
- “Synthesis of Polycyclic 1,2-Dioxanes from Endoperoxides”
Jefford, C.W.; Eschenhof, H.; Bernardinelli, G.
Heterocycles 1998, 47, 283-288.
- “The Photo-Oxygenation of Dihydropyrans. Formation of 1,2-Dioxetanes and 1,2,4-Trioxanes”
Jefford, C.W.; Deheza, M.F.; Wang, J.B.
Heterocycles 1997, 46, 451-462.
- “The Diastereoselective Formation of 1,2,4-Trioxanes and 1,3-Dioxolanes by the reaction of endoperoxides with chiral cyclohexanones”
Jefford, C.W.; Jin, S.-J.; Bernardinelli, G.
Helv. Chim. Acta 1997, 80, 2440-2455.
- “Peroxidic antimalarials”
Jefford, C.W.
in Advances in Drug Research; Advances in Drug Research, 1997; Vol. 29; p. 271-325.
- “Synthesis of Enantiometrically Pure β-Amino Acids Starting from L- and D-Aspartic Acids”
Jefford, C.W.; McNulty, J.
in Enantioselective Synthesis of β-Amino Acids; Juaristi, E. (Ed.) Wiley, 1997; p. 83-104.
- “A QSAR Study of the Antimalarial Activity of Some Synthetic 1,2,4-Trioxanes”
Grigorov, M.; Weber, J.; Tronchet, J.M.J.; Jefford, C.W.; Milhous, W.K.; Maric, D.
J. Chem. Inf. Comput. Sci. 1997, 37, 124-130.
- “cis-Fused Dihydrofurano-1,2,4-trioxanes”
Jefford, C.W.; Jin, S.-j.; Rossier, J.-C.; Kohmoto, S.; Bernardinelli, G.
Heterocycles 1997, 44, 367-378.
- “The Enantioselective Synthesis of β-Amino Acids, their α-hydroxy derivatives, and the N-terminal components of bestatin and microginin”
Jefford, C.W.; McNulty, J.; Lu, Z.-H.; Wang, J.B.
Helv. Chim. Acta 1996, 79, 1203-1216.
- “The Deoxygenation and Isomerization of Artemisinin and Artemether and Their Relevance to Antimalarial Action”
Jefford, C.W.; Vicente, M.G.H.; Jacquier, Y.; Favarger, F.; Mareda, J.; Millasson-Schmidt, P.; Brunner, G.; Burger, U.
Helv. Chim. Acta 1996, 79, 1475-1487.
- “The synthesis of chiral 1-(1H-pyrrole) derivatives”
Jefford, C.W.; de Villedon de Naide, F.; Sienkiewicz, K.
Tetrahedron: Asymmetry 1996, 7, 1069-1076.
- “Heterocyclic templates for assembling α-hydroxy-β-amino acids, sphingosines and indolizidines”
Jefford, C.W.
Pure Appl. Chem. 1996, 68, 799-804.
- “New Cytotoxic Macrolides from the Sponge Fasciospongia rimosa”
Tanaka, J.-i.; Higa, T.; Bernardinelli, G.; Jefford, C.W.
Chem. Lett. 1996, 25, 255-256.
- “Second-generation antimalarial endoperoxides”
Meshnick, S.R.; Jefford, C.W.; Posner, G.H.; Avery, M.A.; Peters, W.
Parasitol. Today 1996, 12, 79-82.
- “Structures and absolute configurations of the marine toxins, latrunculin A and laulimalide”
Jefford, C.W.; Bernardinelli, G.; Tanaka, J.-i.; Higa, T.
Tetrahedron Lett. 1996, 37, 159-162.
- “The design and synthesis of new artemisinin analogues”
Jefford, C.
Jpn. J. Trop. Med. Hyg. 1996, 24, 7-11.
- “Six-membered Rings with 1,2,4-Oxygen or Sulfur Atoms”
Jefford, C.W.
in Comprehensive Heterocyclic Chemistry II; Katritzky, A.R.; Rees, C.W.; Scriven, E.F. (Eds.) Elsevier, 1996; Volume 6; p. 861-899.
- “Short, Enantiospecific Syntheses of Indolizidines 209B and 209D, and Piclavine A from Diethyl-L-Glutamate”
Jefford, C.W.; Sienkiewicz, K.; Thornton, S.R.
Helv. Chim. Acta 1995, 78, 1511-1524.
- “Amplified Asymmetric Dihydroxylation of a Racemic Cyclopentene”
Jefford, C.W.; Timári, G.
J. Chem. Soc., Chem. Commun. 1995, 1501-1502.
- “Comparative modelling studies on 3,6-substituted 1,2,4-trioxan-5-ones”
Jefford, C.W.; Bernardinelli, G.; Josso, M.C.; Morgantini, P.-Y.; Weber, J.
J. Mol. Struct. Theochem 1995, 337, 31-37.
- “Synthesis, Structure, and Antimalarial Activity of Some Enantiomerically Pure, cis-fused cyclopenteno-1,2,4-trioxanes”
Jefford, C.W.; Kohmoto, S.; Jaggi, D.; Timári, G.; Rossier, J.-C.; Rudaz, M.; Barbuzzi, O.; Gérard, D.; Burger, U.; Kamalaprija, P.; Mareda, J.; Bernardinelli, G.; Manzanares, I.; Canfield, C.J.; Feck, S.L.; Robinson, B.L.; Peters, W.
Helv. Chim. Acta 1995, 78, 647-662.
- “The Decomposition of cis-Fused Cyclopenteno-1,2,4-Trioxanes induced by Ferrous Salts and some oxophilic reagents”
Jefford, C.W.; Favarger, F.; Vicente, M.D.G.H.; Jacquier, Y.
Helv. Chim. Acta 1995, 78, 452-458.
- “A Concise Enantioselective Synthesis of N-Morpholinosphingosines from D-Aspartic Acid”
Jefford, C.W.; McNulty, J.; Lu, Z.-H.
J. Chem. Soc., Chem. Commun. 1995, 123-124.
- “A Practical Synthesis of (2S, 3R)-3-Amino-2-methylpentanoic Acid from L-Aspartic Acid”
Jefford, C.W.; McNulty, J.
Helv. Chim. Acta 1994, 77, 2142-2146.
- “Thermolysis and Chemiluminescence of Monocyclic 1,2,4-Trioxan-5-ones”
Jefford, C.W.; Josso, M.C.; Vicente, M.d.G.H.; Hagemann, H.R.; Lovy, D.; Bill, H.
Helv. Chim. Acta 1994, 77, 1851-1860.
- “Concise enantiospecific syntheses of α-hydroxy-β-amino acids and indolizidines of natural origin”
Jefford, C.W.; Lu, Z.-H.; Wang, J.B.
Pure Appl. Chem. 1994, 66, 2075-2078.
- “The osmium-catalyzed asymmetric dihydroxylation of cis-fused cyclopenteno-1,2,4-trioxanes”
Jefford, C.W.; Misra, D.; Dishington, A.P.; Timari, G.; Rossier, J.-C.; Bernardinelli, G.
Tetrahedron Lett. 1994, 35, 6275-6278.
- “A concise synthesis of two pyrroles of marine origin”
Jefford, C.W.; Sienkiewicz, K.; Thornton, S.R.
Tetrahedron Lett. 1994, 35, 6271-6274.
- “Helioxenicins A-C: Diterpenes from the blue coral Heliopora coerulea”
Tanaka, J.-i.; Ogawa, N.; Liang, J.; Higa, T.; deNys, R.; Bowden, B.F.; Carroll, A.R.; Coil, J.C.; Bernardinelli, G.; Jefford, C.W.
Tetrahedron 1994, 50, 9989-9996.
- “The enantiospecific synthesis of (-)-monomorine from L-glutamic ester”
Jefford, C.W.; Sienkiewicz, K.; Thornton, S.R.
Tetrahedron Lett. 1994, 35, 4759-4762.
- “An enantiospecific entry to indolizidines by intramolecular acylation of N-pyrrole esters”
Jefford, C.W.; Thornton, S.R.; Sienkiewicz, K.
Tetrahedron Lett. 1994, 35, 3905-3908.
- “A Concise Synthesis of (E)- and (Z)-Neomanoalides”
Jefford, C.W.; Rossier, J.-C.; Boukouvalas, J.; Huang, P.
Helv. Chim. Acta 1994, 77, 661-667.
- “Computational studies of the structures and properties of potential antimalarial compounds based on the 1,2,4-trioxane ring structure. I. Artemisinin-like molecules”
Bernardinelli, G.; Jefford, C.W.; Maric, D.; Thomson, C.; Weber, J.
Int. J. Quantum Chem., Quantum Biol. Symp. 1994, 52, 117-131.
- “Synthesis, Structure, and Antimalarial Activity of Tricyclic 1,2,4-Trioxanes Related to Artemisinin”
Jefford, C.W.; Velarde, J.A.; Bernardinelli, G.; Bray, D.H.; Warhurst, D.C.; Milhous, W.K.
Helv. Chim. Acta 1993, 76, 2775-2788.
- “A concise diastereospecific synthesis of 3-amino-2-hydroxy acids”
Jefford, C.W.; Wang, J.B.; Lu, Z.-H.
Tetrahedron Lett. 1993, 34, 7557-7560.
- “Short, novel syntheses of lactones and furans of marine origin”
Jefford, C.W.
Gazz. Chim. Ital. 1993, 123, 317-320.
- “Enantiospecific syntheses of indolizidines 167B and 209D”
Jefford, C.W.; Wang, J.B.
Tetrahedron Lett. 1993, 34, 3119-3122.
- “On the Decomposition of 1,2,4-Trioxan-5-ones”
Jefford, C.W.; Vicente, M.G.H.
Heterocycles 1993, 35, 725-729.
- “Bioactive norsesterterpene 1,2-dioxanes from a Thai sponge, Mycale sp”
Tanaka, J.; Higa, T.; Suwanborirux, K.; Kokpol, U.; Bernardinelli, G.; Jefford, C.W.
J. Org. Chem. 1993, 58, 2999-3002.
- “An enantiospecific synthesis of solenopsin A”
Jefford, C.W.; Wang, J.B.
Tetrahedron Lett. 1993, 34, 2911-2914.
- “An enantiospecific synthesis of β-amino acids”
Jefford, C.W.; Wang, J.
Tetrahedron Lett. 1993, 34, 1111-1114.
- “The photo-oxygenation of olefins and the role of zwitterionic peroxides”
Jefford, C.W.
Chem. Soc. Rev. 1993, 22, 59-66.
- “Crystal structure of 1',2',3',4'-tetrahydronaphthaleno[1',2'e]-3,3-dimethyl-1,2,4-trioxine, C13H16O3”
Bernardinelli, G.; Jefford, C.W.; Hatsui, T.; Deheza, M.F.
Z. Kristallogr. 1993, 203, 126-128.
- “A selective, heterogeneous oxidation using a mixture of potassium permanganate and cupric sulfate: (3aS,7aR)-hexahydro-(3S,6R)-dimethyl-2(3H)-benzofuranone”
Jefford, C.W.; Li, Y.; Wang, Y.
Org. Synth. 1993, 71, 207-210.
- “The chemotherapy of rodent malaria. L. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 3: Observations on 'Fenozan-50F', a difluorinated 3,3'-spirocyclopentane 1,2,4-trioxane”
Peters, W.; Robinson, B.L.; Tovey, G.; Rossier, J.-C.; Jefford, C.W.
Ann. Trop. Med. Parasitol. 1993, 87, 111-123.
- “The chemotherapy of rodent malaria. XLIX. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 2: Structure-activity studies on cis-fused cyclopenteno-1,2,4-trioxanes (fenozans) against drug-sensitive and drug-resistant lines of Plasmodium berghei and P. yoelii ssp. NS in vivo”
Peters, W.; Robinson, B.L.; Rossier, J.C.; Misra, D.; Jefford, C.W.
Ann. Trop. Med. Parasitol. 1993, 87, 9-16.
- “The chemotherapy of rodent malaria. XLVIII. The activities of some synthetic 1,2,4-trioxanes against chloroquine-sensitive and chloroquine-resistant parasites. Part 1: Studies leading to the development of novel cis-fused cyclopenteno derivatives”
Peters, W.; Robinson, B.L.; Rossier, J.C.; Jefford, C.W.
Ann. Trop. Med. Parasitol. 1993, 87, 1-7.
- “Cyclopenteno-1,2,4-trioxanes as effective antimalarial surrogates of artemisinin”
Jefford, C.W.; Misra, D.; Rossier, J.C.; Kamalaprija, P.; Burger, U.; Mareda, J.; Bernardinelli, G.; Peters, W.; Robinson, B.L.; Milhous, W.K.; Zhang, F.; Gosser Jr., D.K.; Meshnick, S.R.
in Perspectives in medicinal chemistry; Testa, B. (Ed.) Verlag Helvetica chimica acta: Basel, 1993; p. 459-472.
- “Synthesis of 1,2-dioxanes from an endoperoxide”
Jefford, C.W.; Jin, S.-j.; Kamalaprija, P.; Burger, U.
Tetrahedron Lett. 1992, 33, 7129-7132.
- “Miyakolide: a bryostatin-like macrolide from a sponge, Polyfibrospongia sp”
Higa, T.; Tanaka, J.; Komesu, M.; Garcia Gravalos, D.; Fernandez Puentes, J.L.; Bernardinelli, G.; Jefford, C.W.
J. Am. Chem. Soc. 1992, 114, 7587-7588.
- “Photo-oxygenation of Indene and 1,2-Dihydronaphthalene: Formation of 1,2-Dioxetanes and 1,2,4-Trioxanes”
Jefford, C.W.; Hatsui, T.; Deheza, M.F.; Bernardinelli, G.
CHIMIA 1992, 46, 114-118.
- “The alkylation of silyl enol ethers with SN1-unreactive iodides in the presence of silver trifluoroacetate”
Jefford, C.W.; Sledeski, A.W.; Lelandais, P.; Boukouvalas, J.
Tetrahedron Lett. 1992, 33, 1855-1858.
- “Two New Diterpene Isocyanides from a Sponge of the Family Adocidae”
Sharma, H.A.; Tanaka, J.-i.; Higa, T.; Lithgow, A.; Bernardinelli, G.; Jefford, C.W.
Tetrahedron Lett. 1992, 33, 1593-1596.
- “Torquoselectivity in the electrocyclic conversion of benzocyclobutenes to o-xylylenes”
Jefford, C.W.; Bernardinelli, G.; Wang, Y.; Spellmeyer, D.C.; Buda, A.; Houk, K.N.
J. Am. Chem. Soc. 1992, 114, 1157-1165.
- “Non-heme dioxygenases: a unified mechanistic interpretation of their mode of action”
Jefford, C.W.
Adv. Detailed React. Mech. 1992, 2, 149-187.
- “Reactions of an endoperoxide with chiral ketones. Diastereoselective formation of 1,2,4-trioxanes and 1,3-dioxolanes”
Jefford, C.W.; Jin, S.-j.; Bernardinelli, G.
Tetrahedron Lett. 1991, 32, 7243-7246.
- “The thermal decomposition of some 1,2,4-trioxanes”
Jefford, C.W.; Jaber, A.; Boukouvalas, J.; Tissot, P.
Tetrahedron Lett. 1991, 188, 337-342.
- “The Synthesis of 1,2,4-Trioxan-5-ones”
Jefford, C.W.; Currie, J.; Richardson, G.D.; Rossier, J.-C.
Helv. Chim. Acta 1991, 74, 1239-1246.
- “Short, enantiogenic syntheses of (-)-indolizidine 167B and (+)-monomorine”
Jefford, C.W.; Tang, Q.; Zaslona, A.
J. Am. Chem. Soc. 1991, 113, 3513-3518.
- “The Synthesis of Boronolide”
Jefford, C.W.; Moulin, M.-C.
Helv. Chim. Acta 1991, 74, 336-342.
- “1,2,4-Trioxan-5-ones, a new class of endoperoxides: structures of three representative derivatives”
Bernardinelli, G.; Jefford, C.W.; Richardson, G.D.; Rossier, J.C.
Acta Crystallogr., Sect. C: Cryst. Struct. Commun. 1991, C47, 388-392.
- “Assignment of the configuration of disubstituted 1,3-dienes by nuclear Overhauser effect measurements”
Jefford, C.W.; Wang, Y.; Houk, K.N.
J. Org. Chem. 1991, 56, 856-858.
- “1,2,4-Trioxanes, the chemistry of a new class of saturated heterocycles”
Jefford, C.W.
Stud. Surf. Sci. Catal. 1991, 66, 555-564.
- “trans-3,6-Dinonyl-1,2,4,5-tetroxane”
Bernardinelli, G.; Jefford, C.W.; Jaber, A.; Boukouvalas, J.
Acta Crystallogr., Sect. C: Cryst. Struct. Commun. 1990, C46, 2476-2478.
- “A Practical, Versatile Approach to Marine Furanosesquiterpenes. Synthesis of Siphonodictidine and Pleraplysillin-2”
Jefford, C.W.; Huang, P.-Z.; Rossier, J.-C.; Sledeski, A.W.; Boukouvalas, J.
Synlett 1990, 745-746.
- “Detection of carbonyl oxide from singlet p-nitrophenylchlorocarbene and oxygen”
Liu, M.T.H.; Bonneau, R.; Jefford, C.W.
J. Chem. Soc., Chem. Commun. 1990, 1482-1483.
- “Structure of synthetic bromobeckerelide. A case of diastereomeric selection in the solid state”
Jefford, C.W.; Jaggi, D.; Boukouvalas, J.; Bernardinelli, G.
Acta Crystallogr., Sect. C: Cryst. Struct. Commun. 1990, 46, 1879-1881.
- “A short route to furanosesquiterpenes using a new siloxyfuran building block. The synthesis of freelingnite and dehydrolasiosperman”
Jefford, C.W.; Sledeski, A.W.; Rossier, J.-C.; Boukouvalas, J.
Tetrahedron Lett. 1990, 31, 5741-5744.
- “The Reaction of Singlet Oxygen with Adamantylideneadamantane Mediated by Rose Bengal”
Jefford, C.W.; Jimenez Estrada, M.; Barchietto, G.; Berclaz, T.; Geoffroy, M.
Helv. Chim. Acta 1990, 73, 1653-1658.
- “A New Method for the Synthesis of gem-Dihydroperoxides”
Jefford, C.W.; Li, Y.; Jaber, A.; Boukouvalas, J.
Synth. Commun. 1990, 20, 2589-2596.
- “Regioselective 2-acylation of N-substituted pyrroles by intramolecular delivery”
Jefford, C.W.; Tang, Q.; Boukouvalas, J.
Tetrahedron Lett. 1990, 31, 995-998.
- “A Short, Simple Synthesis of (±)-Monomorine”
Jefford, C.W.; Tang, Q.; Zaslona, A.
Helv. Chim. Acta 1989, 72, 1749-1752.
- “Sulfur-containing polybromoindoles from the red alga Laurencia brongniartii”
Tanaka, J.; Higa, T.; Bernardinelli, G.; Jefford, C.W.
Tetrahedron 1989, 45, 7301-7310.
- “The regio- and stereo-controlled synthesis of cis-p-menth-3-ene-1,2-diol by means of a 1,2,4-trioxane intermediate”
Jefford, C.W.; Jaber, A.; Boukouvalas, J.
J. Chem. Soc., Chem. Commun. 1989, 1916-1918.
- “In vitro effects of three new 1,2,4-trioxanes (pentatroxane, thiahexatroxane, and hexatroxanone) on Toxoplasma gondii.”
Chang, H.R.; Jefford, C.W.; Pechère, J.C.
Antimicrob. Agents Chemother. 1989, 33, 1748-1752.
- “Synthesis of cis and trans Whisky and Cognac lactones by the regiocontrolled alkylation of 2-(trimethylsiloxy)furan”
Jefford, C.W.; Sledeski, A.W.; Boukouvalas, J.
Helv. Chim. Acta 1989, 72, 1362-1370.
- “Synthesis of tricyclic arteannuin-like compounds”
Jefford, C.W.; Velarde, J.; Bernardinelli, G.
Tetrahedron Lett. 1989, 30, 4485-4488.
- “Batzellines A, B, and C. Novel pyrroloquinoline alkaloids from the sponge Batzella Sp.”
Sakemi, S.; Sun, H.H.; Jefford, C.W.; Bernardinelli, G.
Tetrahedron Lett. 1989, 30, 2517-2520.
- “Total synthesis of bromobeckerelide”
Jefford, C.W.; Jaggi, D.; Boukouvalas, J.
Tetrahedron Lett. 1989, 30, 1237-1240.
- “1,2,4-Trioxanes as Masked, Dual Purpose, Functional Groups”
W. Jefford, C.; Rossier, J.-C.; Boukouvalas, J.
Heterocycles 1989, 28, 673-676.
- “New methodology for the synthesis of biologically active lactones”
Jefford, C.W.; Jaggi, D.; Sledeski, A.W.; Boukouvalas, J.
in Studies in Natural Products Chemistry vol 3; Atta-ur-Rahman, F. (Ed.) Elsevier: Amsterdam, 1989; Part b; p. 157-171.
- “Mechanistic and Synthetic Studies on the Formation of 1,2,4-Trioxanes Related to Arteannuin. Photooxygenation of a bicyclic dihydropyran”
Jefford, C.W.; Wang, Y.; Bernardinelli, G.
Helv. Chim. Acta 1988, 71, 2042-2052.
- “Regioselective aldol condensations of boron and tin furanolates with aldehydes: an improved synthesis of 2-(1'-hydroxyalkyl)butenolides”
Jefford, C.W.; Jaggi, D.; Boukouvalas, J.
J. Chem. Soc., Chem. Commun. 1988, 1595-1596.
- “Itomanindoles A and B. Methylsulfinylindoles from Laurencia Brongniartii”
Tanaka, J.; Higa, T.; Bernardinelli, G.; Jefford, C.W.
Tetrahedron Lett. 1988, 29, 6091-6094.
- “Synthesis of New 1,2,4-Trioxanes and their Antimalarial Activity”
Jefford, C.W.; McGoran, E.C.; Boukouvalas, J.; Richardson, G.; Robinson, B.L.; Peters, W.
Helv. Chim. Acta 1988, 71, 1805-1812.
- “Brianthein V, a New Cytotoxic and Antiviral Diterpene Isolated from Briareum asbestinum”
Coval, S.J.; Cross, S.; Bernardinelli, G.; Jefford, C.W.
J. Nat. Prod. 1988, 51, 981-984.
- “A Vibrational Study of Some 1,2,4-Trioxanes”
Mohnhaupt, M.; Hagemann, H.; Perler, J.-P.; Bill, H.; Boukouvalas, J.; Rossier, J.-C.; Jefford, C.W.
Helv. Chim. Acta 1988, 71, 992-999.
- “Selective, heterogeneous oxidation of alcohols and diols with potassium permanganate”
Jefford, C.W.; Wang, Y.
J. Chem. Soc., Chem. Commun. 1988, 634-635.
- “Efficient Preparation of 1,2,4,5-Tetroxanes from Bis(trimethylsilyl) Peroxide and Carbonyl Compounds”
Jefford, C.W.; Jaber, A.; Boukouvalas, J.
Synthesis 1988, 391-393.
- “Electronic control of the stereoselectivities of electrocyclic reactions of cyclobutenes against incredible steric odds”
Houk, K.N.; Spellmeyer, D.C.; Jefford, C.W.; Rimbault, C.G.; Wang, Y.; Miller, R.D.
J. Org. Chem. 1988, 53, 2125-2127.
- “Regioselective alkylation of 2-trimethylsiloxyfuran; direct access to 4-substituted but-2-en-4-olides”
Jefford, C.W.; Sledeski, A.W.; Boukouvalas, J.
J. Chem. Soc., Chem. Commun. 1988, 364-365.
- “New applications of peroxides and their equivalents for synthesizing oxygen heterocycles”
Jefford, C.W.
Stud. Org. Chem. (Amsterdam) 1988, 33, 13-22.
- “Manzamine B and C, two novel alkaloids from the sponge haliclona sp.”
Sakai, R.; Kohmoto, S.; Higa, T.; Jefford, C.W.; Bernardinelli, G.
Tetrahedron Lett. 1987, 28, 5493-5496.
- “A mild and efficient preparation of cis-1,2-diols from 1,2,4-trioxanes”
Jefford, C.W.; Rossier, J.-C.; Boukouvalas, J.
J. Chem. Soc., Chem. Commun. 1987, 1593-1594.
- “A simple, general distereoselective synthesis of 5-hydroxyalkylbutan-4-olides”
Jefford, C.W.; Wang, Y.
J. Chem. Soc., Chem. Commun. 1987, 1513-1514.
- “Diastereoselectivity in the directed aldol condensation of 2-trimethylsiloxyfuran with aldehydes. A stereodivergent route to threo and erythro δ-hydroxy-γ-lactones”
Jefford, C.W.; Jaggi, D.; Boukouvalas, J.
Tetrahedron Lett. 1987, 28, 4037-4040.
- “The synthesis of (±)-cavernosine”
Jefford, C.W.; Jaggi, D.; Bernardinelli, G.; Boukouvalas, J.
Tetrahedron Lett. 1987, 28, 4041-4044.
- “Electrophile-induced rearrangement of 1,2,4-trioxanes. Formation of 1-benzofuran and 2H-1-benzopyrans”
Jefford, C.W.; Rossier, J.-C.; Boukouvalas, J.
J. Chem. Soc., Chem. Commun. 1987, 713-714.
- “Structures of an ozonide, a spirocyclic acetal and a hydroperoxide derived from cyclopenteno-1,2,4-trioxanes”
Bernardinelli, G.; Jefford, C.W.; Boukouvalas, J.; Jaggi, D.; Kohmoto, S.
Acta Crystallogr., Sect. C: Cryst. Struct. Commun. 1987, 43, 701-705.
- “The reaction of adamantylideneadamantane with singlet oxygen mediated by rose bengal and charge transfer complexes”
Jefford, C.W.; Estrada, M.J.; Barchietto, G.
Tetrahedron 1987, 43, 1737-1745.
- “A direct synthesis of (±)-eldanolide via the highly regioselective prenylation of 2-trimethylsiloxyfuran”
Jefford, C.W.; Sledeski, A.W.; Boukouvalas, J.
Tetrahedron Lett. 1987, 28, 949-950.
- “Mechanistic and synthetic studies pertaining to 1,2,4-trioxanes”
Jefford, C.W.; Ferrufino, M.; Hatsui, T.; Favarger, F.; Jaggi, D.; Rossier, J.-C.; Ferro, S.; Velarde, J.; Kohmoto, S.; et al., .
Stud. Org. Chem. (Amsterdam) 1987, 31, 113-120.
- “Intramolecular Carbenoid Reactions of Pyrrole Derivatives. A Total Synthesis of (±)-Ipalbidine”
Jefford, C.W.; Kubota, T.; Zaslona, A.
Helv. Chim. Acta 1986, 69, 2048-2061.
- “Eliminative ring fission of 1,2,4-trioxan-5-ones. A new approach to α-keto acids”
Jefford, C.W.; Rossier, J.-C.; Boukouvalas, J.
J. Chem. Soc., Chem. Commun. 1986, 1701-1702.
- “The Formation of Bridged Bicyclic 1,2,4-Trioxanes by Intramolecular Capture of β-Hydroperoxy Cations”
Jefford, C.W.; Favarger, F.; Ferro, S.; Chambaz, D.; Bringhen, A.; Bernardinelli, G.; Boukouvalas, J.
Helv. Chim. Acta 1986, 69, 1778-1786.
- “Manzamine A, a novel antitumor alkaloid from a sponge”
Sakai, R.; Higa, T.; Jefford, C.W.; Bernardinelli, G.
J. Am. Chem. Soc. 1986, 108, 6404-6405.
- “Venustatriol. A new, anti-viral, triterpene tetracyclic ether from Laurencia venusta”
Sakemi, S.; Higa, T.; Jefford, C.W.; Bernardinelli, G.
Tetrahedron Lett. 1986, 27, 4287-4290.
- “A short, stereodivergent synthesis of the racemic erythro and threo diastereomers of 6-acetoxy-5-hexadecanolide, a mosquito oviposition attractant pheromone”
Jefford, C.W.; Jaggi, D.; Boukouvalas, J.
Tetrahedron Lett. 1986, 27, 4011-4014.
- “Intramolecular Oxygen Transfer on the Ozonolysis of a Diphenylcyclopentene Derivative”
Jefford, C.W.; Boukouvalas, J.; Jaggi, D.; Kohmoto, S.; Bernardinelli, G.
Helv. Chim. Acta 1986, 69, 941-948.
- “The Absolute Configurations and Biogenesis of Some New Halogenated Chamigrenes from the Sea Hare Aplysia dactylomela”
Sakai, R.; Higa, T.; Jefford, C.W.; Bernardinelli, G.
Helv. Chim. Acta 1986, 69, 91-105.
- “New chemistry involving 1,2,4-trioxanes related to Qinghaosu”
Jefford, C.W.; Ferro, S.; Moulin, M.C.; Velarde, J.; Jaggi, D.; Kohmoto, S.; Richardson, G.D.; Godoy, J.; Rossier, J.-C.; Bernardinelli, G.; Boukouvalas, J.
in New Trends in natural products chemistry; Atta-ur-Rahman, .; Le Quesne, P.W. (Eds.) Studies in Organic Chemistry, 26; Overseas Publishers Association: Amsterdam, 1986; p. 163.
- “Chemistry of 1,2,4-trioxanes. Formation of 1,2-diol monoesters”
Jefford, C.W.; Kohmoto, S.; Rossier, J.-C.; Boukouvalas, J.
J. Chem. Soc., Chem. Commun. 1985, 1783-1784.
- “Competitive intramolecular carbenoid reactions of pyrrole derivatives”
Jefford, C.W.; Zaslona, A.
Tetrahedron Lett. 1985, 26, 6035-6038.
- “Acid-Catalyzed Cleavage of 1,4-Dimethyl-1,4-dihydronaphthalene 1,4-Endoperoxide. Reactivity of the Resulting Hydroperoxy Carbocation with Nucleophiles”
Jefford, C.W.; Rossier, J.-C.; Kohmoto, S.; Boukouvalas, J.
Helv. Chim. Acta 1985, 68, 1804-1814.
- “The Reaction of Dihalocarbenes with Quadricyclane”
Jefford, C.W.; Roussilhe, J.; Papadopoulos, M.
Helv. Chim. Acta 1985, 68, 1557-1568.
- “New chemistry of zwitterionic peroxides arising by photooxygenation of enol ethers”
Jefford, C.W.; Boukouvalas, J.; Kohmoto, S.; Bernardinelli, G.
Tetrahedron 1985, 41, 2081-2088.
- “An unusual stereospecific epoxidation with “per-amberlyst 15®””
Jefford, C.W.; Bernardinelli, G.; Rossier, J.-C.; Kohmoto, S.; Boukouvalas, J.
Tetrahedron Lett. 1985, 26, 615-618.
- “A New Approach to Bicyclic 1,3-Dioxolanes: Acetalization of γ-Hydroxycyclohexenones”
Jefford, C.W.; Rossier, J.-C.; Kohmoto, S.; Boukouvalas, J.
Synthesis 1985, 29-31.
- “Determination of the thermal stability of some 1,2-dioxetanes by high-performance liquid chromatography”
Jefford, C.W.; Grant, H.G.; Kohmoto, S.; Boukouvalas, J.
J. Chromatogr., A 1985, 347, 183-187.
- “An improved method for high-performance liquid chromatography of gossypol”
Jefford, C.W.; Grant, H.G.
Anal. Chim. Acta 1985, 166, 311-314.
- “A New Approach to 1,2,4-Trioxanes form Cyclic Allylic Hydroperoxides”
Jefford, C.W.; Jaggi, D.; Kohmoto, S.; Boukouvalas, J.; Bernardinelli, G.
Helv. Chim. Acta 1984, 67, 2254-2260.
- “Effect of Substituents, Solvent, and Temperature on the Reactivity of the Zwitterionic Peroxides Arising from the Photo-Oxygenation of 2-(Methoxymethylidene)- and 2-(Phenoxymethylidene)adamantane”
Jefford, C.W.; Grant, H.G.; Jaggi, D.; Boukouvalas, J.; Kohmoto, S.
Helv. Chim. Acta 1984, 67, 2210-2217.
- “An Efficient Synthesis of 1,4-Dichlorobicyclo[2.2.1]heptan-2-one”
Jefford, C.W.; Barchietto, G.
Synthesis 1984, 1012-1014.
- “Heterogeneous chirality transfer on photooxygenation”
Gerdil, R.; Barchietto, G.; Jefford, C.W.
J. Am. Chem. Soc. 1984, 106, 8004-8005.
- “The Reaction of 4-Hydroperoxy-2,4,6-trimethylcyclohexa-2,5-dienone with Acetaldehyde. Formatino of the Bis(peroxyacetal)”
Jefford, C.W.; Bernardinelli, G.; McGoran, E.C.
Helv. Chim. Acta 1984, 67, 1952-1956.
- “Functionalization of the methyl group of 1,4-dimethyl-1,4-dihydronaphthalene-1,4-endoperoxide”
Jefford, C.W.; Rossier, J.-C.; Kohmoto, S.; Boukouvalas, J.
J. Chem. Soc., Chem. Commun. 1984, 1496-1497.
- “Dynamic molecular modeling. The case of rearranging polycyclic C8H9 cations”
Jefford, C.W.; Mareda, J.; Combremont, J.J.; Weber, J.
CHIMIA 1984, 38, 354-356.
- “The Reaction of Singlet Oxygen with 1,3-Dimethylindole in the Presence of Aldehydes. Formation of 1,2,4-Trioxanes”
Jefford, C.W.; Jaggi, D.; Boukouvalas, J.; Kohmoto, S.; Bernardinelli, G.
Helv. Chim. Acta 1984, 67, 1104-1111.
- “Reactions of cyclic peroxides with aldehydes and ketones catalysed by trimethylsilyl trifluoromethanesulphonate. An efficient synthesis of 1,2,4-trioxanes”
Jefford, C.W.; Boukouvalas, J.; Kohmoto, S.
J. Chem. Soc., Chem. Commun. 1984, 523-524.
- “High-performance liquid chromatography of some novel diastereomeric tricyclic 1,2,4-trioxanes”
Jefford, C.W.; Boukouvalas, J.; Kohmoto, S.; Grant, H.G.
Anal. Chim. Acta 1984, 157, 199-202.
- “Intramolecular Carbenoid Reactions of Pyrrole Derivatives Efficient Syntheses of Pyrrolizinone and Dihydroindolizinone”
Jefford, C.W.; Johncock, W.
Helv. Chim. Acta 1983, 66, 2666-2671.
- “A New Reaction of 1,2-Dioxetanes. Formation of 1,2,4-Trioxanes from Aldehydes”
Jefford, C.W.; Boukouvalas, J.; Kohmoto, S.
Helv. Chim. Acta 1983, 66, 2615-2620.
- “The reaction of trimethylsilyl α-trimethylsilylperoxy esters with ketones and aldehydes. A simple, efficient synthesis of 1,2,4-trioxan-5-ones”
Jefford, C.W.; Rossier, J.-C.; Richardson, G.D.
J. Chem. Soc., Chem. Commun. 1983, 1064-1065.
- “Reaction of singlet oxygen with enol ethers in the presence of acetaldehyde. Formation of 1,2,4-trioxanes”
Jefford, C.W.; Kohmoto, S.; Boukouvalas, J.; Burger, U.
J. Am. Chem. Soc. 1983, 105, 6498-6499.
- “Reaction of bicyclic endo peroxides with carbonyl compounds. A new approach to 1,2,4-trioxanes”
Jefford, C.W.; Jaggi, D.; Boukouvalas, J.; Kohmoto, S.
J. Am. Chem. Soc. 1983, 105, 6497-6498.
- “Ionization potentials, electron affinities, and molecular orbitals of 2-substituted norbornadienes. Theory of 1,2 and homo-1,4 carbene cycloaddition selectivities”
Houk, K.N.; Rondan, N.G.; Paddon-Row, M.N.; Jefford, C.W.; Huy, P.T.; Burrow, P.D.; Jordan, K.D.
J. Am. Chem. Soc. 1983, 105, 5563-5569.
- “Evidence for homoquadricyclene, a possible carbon ylide”
Jefford, C.W.; Rossier, J.-C.; Zuber, J.A.; Kennard, O.; Cruse, W.B.T.
Tetrahedron Lett. 1983, 24, 181-184.
- “Rearrangements Involving C8H8F-Cations of the Cage Type”
Jefford, C.W.; Mareda, J.; Blaudzun, J.-P.; Burger, U.
Helv. Chim. Acta 1982, 65, 2476-2480.
- “Sigmatropic Rearrangements Accompanying the Addition of Dichlorocarbene to Norbornadiene”
Jefford, C.W.; Bernardinelli, G.; Rossier, J.-C.; Zuber, J.A.
Helv. Chim. Acta 1982, 65, 1467-1469.
- “A Short, Simple Synthesis of Dihalo and Trihalobarbaralanes”
Jefford, C.W.; Rossier, J.-C.; Zuber, J.A.
Angew. Chem. Int. Ed. Engl. 1982, 21, 1186-1192.
- “A Simple Synthesis of Di- and Trihalobarbaralanes”
Jefford, C.W.; Rossier, J.-C.; Zuber, J.A.
Angew. Chem. Int. Ed. Engl. 1982, 21, 549.
- “Synthesis and Photo-oxygenation of Some Substituted 1-Benzyl-3,4-dihydroisoquinolines. Mechanism of Enamine Photo-oxygenation”
Martin, N.H.; Jefford, C.W.
Helv. Chim. Acta 1982, 65, 762-774.
- “The Effect of Solvent on Competing Hydroperoxide and Dioxetane Formation on Photo-Sensitized Oxygenation of Olefins”
Jefford, C.W.; Kohmoto, S.
Helv. Chim. Acta 1982, 65, 133-136.
- “Effect of substituents on the homo-1,4 addition of difluorocarbene to norbornadienes”
Jefford, C.W.; Huy, P.T.
Tetrahedron Lett. 1982, 23, 391-394.
- “Highly active nitroaromatic antiparasitic drugs”
Jefford, C.W.; Cadby, P.A.; Smith, L.C.; Pipe, D.F.
Pharmazie 1982, 37, 395-402.
- “New rearrangements and structures implicating small rings”
Jefford, C.W.; Zuber, J.A.
Rev. Port. Quim. 1982, 24, 1-6.
- “The Hydroperoxidation of Olefins by Singlet Oxygen. Validity of the zwitterionic peroxide model”
Jefford, C.W.
Helv. Chim. Acta 1981, 64, 2534-2539.
- “Self-Sensitized Photo-Oxygenation of 1-Benzyl-3, 4-dihydroisoquinolines”
Martin, N.H.; Jefford, C.W.
Helv. Chim. Acta 1981, 64, 2189-2192.
- “Evaluation of models for the mechanism of action of 4-hydroxyphenylpyruvate dioxygenase”
Jefford, C.W.; Cadby, P.A.
Experientia 1981, 37, 1134-1137.
- “Evidence for a charge-transfer mechanism in the photo-oxygenation of an enamine”
Martin, N.H.; Jefford, C.W.
Tetrahedron Lett. 1981, 22, 3949-3952.
- “Syn regioselectivity of the hydroperoxidation of cyclo-alkenes with singlet oxygen”
Jefford, C.W.; Rimbault, C.G.
Tetrahedron Lett. 1981, 22, 91-94.
- “Molecular mechanisms of enzyme-catalyzed dioxygenation (an interdisciplinary review)”
Jefford, C.W.; Cadby, P.A.
Prog. Chem. Org. Nat. Prod. 1981, 40, 191-265.
- “The deceptive rearrangement of a C8H9 cation of the cage type”
Jefford, C.W.; Rossier, J.-C.; Zuber, J.A.; Suri, S.C.; Mehta, G.
Tetrahedron Lett. 1980, 21, 4081-4084.
- “The role of entropic and electronic factors in controlling homo-1,4 addition of dihalocarbenes to norbornadiene-type molecules”
Jefford, C.W.; de los Heros, V.; Gehret, J.-C.E.; Wipff, G.
Tetrahedron Lett. 1980, 21, 1629-1632.
- “The predictable rearrangement of tetracyclic C8H9 cations”
Jefford, C.W.; de los Heros, V.
Tetrahedron Lett. 1980, 21, 913-916.
- “Competing cheletropic reactions of difluorocarbene with various 2-substituted norbornadienes”
Jefford, C.W.; Huy, P.T.
Tetrahedron Lett. 1980, 21, 755-758.
- “Chemistry of Superoxide Ion as Revealed by the Differential Oxidation of Arylpyruvates”
Jefford, C.W.; Cadby, P.A.
Helv. Chim. Acta 1979, 62, 1866-1871.
- “A definitive investigation of the reaction of cyclopentadiene with cis-3,4-dichlorocyclobutene: A literature correction”
Warrener, R.N.; Johnson, R.P.; Jefford, C.W.; Ralph, D.A.
Tetrahedron Lett. 1979, 20, 2939-2942.
- “The predictable behaviour of cations deriving from endo-4-chlorotetracyclo[3.3.0.0.2,8O.3,6]octane”
Jefford, C.W.; Genevay-Höck, S.; Delay, A.; Mareda, J.; Burger, U.
Tetrahedron Lett. 1979, 20, 2549-2552.
- “The transformation of difluorocarbene into 3,3-diflurocyclopropene”
Jefford, C.W.; Acar, M.; Delay, A.; Mareda, J.; Burger, U.
Tetrahedron Lett. 1979, 20, 1913-1916.
- “A MINDO/3 study of the bridged pyramidal C8H9 cation and its congeners”
Jefford, C.W.; Mareda, J.; Perlberger, J.C.; Burger, U.
J. Am. Chem. Soc. 1979, 101, 1370-1378.
- “The role of zwitterionic peroxides in controlling hydroperoxidation”
Jefford, C.W.
Tetrahedron Lett. 1979, 20, 985-988.
- “Synthesis of 7,7-dimethylnorbornadiene”
Jefford, C.W.; Wallace, T.W.; Nguyen, T.H.C.; Rimbault, C.G.
J. Org. Chem. 1979, 44, 689-691.
- “Addition of dihalocarbenes to quadricyclane”
Jefford, C.W.; Gehret, J.-C.E.; de los Heros, V.
Bull. Soc. Chim. Belg. 1979, 88, 973-978.
- “Abnormal Birch reduction of dichloro derivatives of C8H10 hydrocarbons”
Jefford, C.W.; de los Heros, V.
Bull. Soc. Chim. Belg. 1979, 88, 969-972.
- “Oxygenation of methyl p-methoxyphenylpyruvate. α-Keto-β-peroxylactone and dioxetanol intermediates.”
Jefford, C.W.; Knöpfel, W.; Cadby, P.A.
Tetrahedron Lett. 1978, 19, 3585-3588.
- “Reaction of singlet oxygen with a norbornadienol ether. Intramolecular interception of a zwitterionic peroxide”
Jefford, C.W.; Rimbault, C.G.
J. Am. Chem. Soc. 1978, 100, 6515-6516.
- “Reaction of singlet oxygen with norbornenyl ethers. Characterization of dioxetanes and evidence for zwitterionic peroxide precursors”
Jefford, C.W.; Rimbault, C.G.
J. Am. Chem. Soc. 1978, 100, 6437-6445.
- “Oxygenation of 3-aryl-2-hydroxyacrylic acids. The question of linear fragmentation vs. cyclization and cleavage of intermediates”
Jefford, C.W.; Knoepfel, W.; Cadby, P.A.
J. Am. Chem. Soc. 1978, 100, 6432-6436.
- “The role of singlet oxygen as reagent in the dye-sensitized photo-oxygenation of α-ketocarboxylic acids”
Jefford, C.W.; Exarchou, A.; Cadby, P.A.
Tetrahedron Lett. 1978, 19, 2053-2056.
- “Reaction of singlet oxygen with 2-methylnorbornadiene and 2-methylidenenorbornene. Evaluation of electronic and steric effects on the course of hydroperoxidation”
Jefford, C.W.; Rimbault, C.G.
J. Org. Chem. 1978, 43, 1908-1912.
- “Characterization of a dioxetane deriving from norbornene and evidence for its zwitterionic peroxide precursor”
Jefford, C.W.; Rimbault, C.G.
J. Am. Chem. Soc. 1978, 100, 295-296.
- “The Reaction of Biadamantylidene with Singlet Oxygen in the Presence of Dyes [1]”
Jefford, C.W.; Boschung, A.F.
Helv. Chim. Acta 1977, 60, 2673-2685.
- “The reaction of phosphorus ylids with singlet oxygen”
Jefford, C.W.; Barchietto, G.
Tetrahedron Lett. 1977, 18, 4531-4534.
- “A convenient large-scale preparation of benzobarrelene”
Johnson, R.P.; Exarchou, A.; Jefford, C.W.; Hahn, R.C.
J. Org. Chem. 1977, 42, 3758-3759.
- “Evidence for an intermediate in the reaction of singlet oxygen with a silylenol ether”
Jefford, C.W.; Rimbault, C.G.
Tetrahedron Lett. 1977, 18, 2375-2378.
- “An improved procedure for the preparation of bicyclo[2.2.2]octa-2,5,7-triene (barrelene)”
Jefford, C.W.; Wallace, T.W.; Acar, M.
J. Org. Chem. 1977, 42, 1654-1655.
- “The dye-sensitized photo-oxygenation of biadmantylidene”
Jefford, C.W.; Boschung, A.F.
Tetrahedron Lett. 1976, 17, 4771-4774.
- “The Reaction of Singlet and Triplet Oxygen with 2-Phenylnorbornene”
Jefford, C.W.; Boschung, A.F.; Rimbault, C.G.
Helv. Chim. Acta 1976, 59, 2542-2550.
- “The Reaction of Difluorocarbene with Bicyclo[2.2.2]octadiene”
Jefford, C.W.; Delay, A.; Wallace, T.W.; Burger, U.
Helv. Chim. Acta 1976, 59, 2355-2361.
- “Syntheses and rearrangements of cage molecules related to cubane”
Jefford, C.W.
J. Chem. Educ. 1976, 53, 477-482.
- “The reaction of singlet oxygen with 2-phenylcycloalkenes possessing small and common rings”
Jefford, C.W.; Rimbault, C.G.
Tetrahedron Lett. 1976, 17, 2479-2482.
- “The Clemmensen Reduction of α,β-Unsaturated Ketones”
Jefford, C.W.; Boschung, A.F.
Helv. Chim. Acta 1976, 59, 962-969.
- “Cheletropic reactions of fluorocarbenes with norbornadienes”
Jefford, C.W.; Mareda, J.; Gehret, J.C.E.; Kebengele, T.; Graham, W.D.; Burger, U.
J. Am. Chem. Soc. 1976, 98, 2585-2593.
- “Cheletropic reactions of dichloro- and dibromocarbenes with norbornadiene”
Jefford, C.W.; de los Heros, V.; Burger, U.
Tetrahedron Lett. 1976, 17, 703-706.
- “Reaction of singlet oxygen with α-ketocarboxylic acids. Oxidative decarboxylation and peroxyacid formation”
Jefford, C.W.; Boschung, A.F.; Bolsman, T.A.B.M.; Moriarty, R.M.; Melnick, B.
J. Am. Chem. Soc. 1976, 98, 1017-1018.
- “Cheletropic additions of difluoro and dichlorocarbenes to hindered norbornadienes”
Jefford, C.W.; Graham, W.D.; Burger, U.
Tetrahedron Lett. 1975, 16, 4717-4720.
- “Organic Chemistry: a Problems Approach”
Moriarty, R.M.; Jefford, C.W.
Benjamin Publishing: Menlo Park (Calif.), 1975, 652 pp.
- “An Anomalous Oxidation of β-Pinene”
Jefford, C.W.; Roussel, A.; Evans, S.M.
Helv. Chim. Acta 1975, 58, 2151-2160.
- “Electrocyclic closure of bicyclo[4.2.1]nona-2,4-dienes. Photochemical steering by a heavy atom effect”
Jefford, C.W.; Delay, F.
J. Am. Chem. Soc. 1975, 97, 2272-2273.
- “The thermal stability of exo and endo tricyclo[3.2.1.02,4]oct-6-enes and their relevance to the cyclo-addition of cyclopropenes to cyclopentadiene.”
Jefford, C.W.; Gehret, J.-C.E.; Mareda, J.; Kabengele, n.; Graham, W.D.; Burger, U.
Tetrahedron Lett. 1975, 16, 823-826.
- “The Reaction of Singlet Oxygen with Norbornene”
Jefford, C.W.; Boschung, A.F.
Helv. Chim. Acta 1974, 57, 2257-2261.
- “Reaction of Singlet Oxygen with 2-Methylnorborn-2-ene, 2-Methylidenenorbornane, and their 7,7-Dimethyl Derivatives. The transition state geometry for hydroperoxidation”
Jefford, C.W.; Boschung, A.F.
Helv. Chim. Acta 1974, 57, 2242-2257.
- “Synthesis and structural analysis of a series of 1-methylbicyclo[3.2.1]octanes. Stereochemistry of the 4JHH coupling”
Zahra, J.P.; Casanova, J.; Waegeli, B.; Gassend, R.; Jefford, C.W.
Bull. Soc. Chim. Fr. 1974, 2247-2255.
- “The thermal electrocyclic opening of cyclobut-2-enols. Directed conrotations and stable dienols.”
Jefford, C.W.; Boschung, A.F.; Rimbault, C.G.
Tetrahedron Lett. 1974, 15, 3387-3390.
- “Additions of fluorocarbenes to norbornadiene by linear cheletropic reaction”
Jefford, C.W.; Kabengele, n.; Kovacs, J.; Burger, U.
Tetrahedron Lett. 1974, 15, 257-260.
- “Die Addition von Fluorcarbenen an Norbornadien: Eine Homo-1,4-addition”
Jefford, C.W.; Kabengele, n.; Kovacs, J.; Burger, U.
Helv. Chim. Acta 1974, 57, 104-113.
- “The synthesis of 7,7-difluoronorbornadiene and its quadricyclane isomer”
Jefford, C.W.; Burger, U.; Broeckx, W.; Gehret, J.-C.E.
Tetrahedron Lett. 1973, 14, 5187-5190.
- “The Reaction of Singlet Oxygen with α- and β-Pinenes”
Jefford, C.W.; Boschung, A.F.; Moriarty, R.M.; Rimbault, C.G.; Laffer, M.H.
Helv. Chim. Acta 1973, 56, 2649-2659.
- “Barrier to inversion of dicoordinated sulfur. Erroneous report of stereoisomerism in a dithiin”
Moriarty, R.M.; Chien, C.C.; Jefford, C.W.
Tetrahedron Lett. 1973, 14, 4429-4431.
- “An unusual diversion of the course of birch reduction of polychlorinated olefins. Formation of cyclopropanes”
Jefford, C.W.; Delay, F.
Tetrahedron Lett. 1973, 14, 3639-3642.
- “Reductive dechlorination of gem-chlorofluorocyclopropanes with lithium aluminium hydride. A stereoselective process.”
Jefford, C.W.; Burger, U.; Laffer, M.H.; Kabengele, n.
Tetrahedron Lett. 1973, 14, 2483-2486.
- “Site selection of metal complexation in the semibullvalene skeleton. Exigencies of palladation”
Moriarty, R.M.; Yeh, C.-L.; Chen, K.-N.; Yeh, E.-L.; Ramey, K.C.; Jefford, C.W.
J. Am. Chem. Soc. 1973, 95, 4756-4758.
- “Synthesis of Bridged Bicyclic Molecules using Halocarbenes. Derivatives of bicyclo[4.2.1]nonane”
Jefford, C.W.; Burger, U.; Delay, F.
Helv. Chim. Acta 1973, 56, 1083-1096.
- “Spectroscopy and structure elucidation. Coordinated experimental exercises in advanced organic chemistry”
Jefford, C.W.; McCreadie, R.; Muller, P.; Pfyffer, J.
J. Chem. Educ. 1973, 50, 181-185.
- “Reductive dehalogenation of alkyl halides with lithium aluminum hydride. Reappraisal of the scope of the reaction”
Jefford, C.W.; Kirkpatrick, D.; Delay, F.
J. Am. Chem. Soc. 1972, 94, 8905-8907.
- “Exo-endo steric impediment in norbornene. Specification of the transition state for the reaction of singlet oxygen with 2-methylnorborn-2-ene and 2-methylenenorbornane”
Jefford, C.W.; Laffer, M.H.; Boschung, A.F.
J. Am. Chem. Soc. 1972, 94, 8904-8905.
- “Cyclopropyl-solvolyse. Fluorwasserstoff als austretende gruppe”
Jefford, C.W.; Kabengele, A.N.; Burger, U.
Tetrahedron Lett. 1972, 13, 4799-4802.
- “Reaction of 2-Methylenenorbornane with N-Bromosuccinimide”
Jefford, C.W.; Wojnarowski, W.
Helv. Chim. Acta 1972, 55, 2244-2252.
- “The Reaction of Bicyclo [3.2.1] octenyl Halides with Metal Hydrides”
Jefford, C.W.; Sweeney, A.; Delay, F.
Helv. Chim. Acta 1972, 55, 2214-2227.
- “Exo-endo steric impediment in norbornene. Electrocyclic closure in bicyclo[4.2.1]nona-2,4-dienes”
Jefford, C.W.; Delay, F.
J. Am. Chem. Soc. 1972, 94, 4794-4795.
- “The Reaction of Phenyl(trichloromethyl)mercury with Substituted Norbornenes”
Jefford, C.W.; Hill, D.T.; Goré, J.; Waegell, B.
Helv. Chim. Acta 1972, 55, 790-798.
- “Bromohydrin formation in dimethyl sulfoxide. V. Reaction of norbornene”
Dalton, D.R.; Rodebaugh, R.K.; Jefford, C.W.
J. Org. Chem. 1972, 37, 362-367.
- “Bridgehead reactivity. An experiment in organic chemistry”
Jefford, C.W.; McCreadie, R.; Müller, P.; Siegfried, B.
J. Chem. Educ. 1971, 48, 708-710.
- “Aromatic transition states and the reactivity of geometrically well-defined molecules”
Jefford, C.W.; Burger, U.
CHIMIA 1971, 25, 297-307.
- “Reaction of Bicyclo[3.2.1]octenols with Thionyl Chloride. Preliminary paper”
Jefford, C.W.; Gunsher, J.A.
Helv. Chim. Acta 1971, 54, 1482-1483.
- “The Synthesis of 7,7-Difluoronorbornene. Preliminary communication”
Jefford, C.W.; Broeckx, W.
Helv. Chim. Acta 1971, 54, 1479-1481.
- “Bicyclo[3.2.1]octan-3-one”
Jefford, C.W.; Gunsher, J.; Hill, D.T.; Brun, P.; Le Gras, J.; Waegell, B.
Org. Synth. 1971, 51, 60-65.
- “Bending effects in constrained cyclohexane derivatives”
Jefford, C.W.; Burger, U.
CHIMIA 1970, 24, 385-388.
- “Stereochemistry of brominated derivatives of 6,6-dimethylbicyclo[3.1.1]heptan-3-one (isonopinone). The anti-reflex effect”
Baretta, A.; Jefford, C.W.; Waegell, B.
Bull. Soc. Chim. Fr. 1970, 11, 3899-3908.
- “Conformational study of 6,6-dimethylbicyclo[3.1.1]heptanes using NMR. Configuration and conformation of isonopinols, nopinols, and isonopinone”
Baretta, A.; Jefford, C.W.; Waegell, B.
Bull. Soc. Chim. Fr. 1970, 11, 3985-3993.
- “Addition of halocarbenes to bridged bicyclic olefins”
Jefford, C.W.
CHIMIA 1970, 24, 357-363.
- “Stereochemical requirements for long-range coupling between protons in α-halocyclohexanones”
Jefford, C.W.; Waegell, B.
Bull. Soc. Chim. Belg. 1970, 79, 427-436.
- “Reaction of 2-Methylnorborn-2-ene with N-Bromosuccinimide [1]”
Jefford, C.W.; Wojnarowski, W.
Helv. Chim. Acta 1970, 53, 1194-1202.
- “Fluorine NMR. Spectra of conformationally constrained Gem-difluorocyclohexanes”
Jefford, C.W.; Hill, D.T.; Ramey, K.C.
Helv. Chim. Acta 1970, 53, 1184-1194.
- “Flexional Effects in Bridged Bicyclic Molecules Progressive Flattening of Chair Cyclohexane”
Jefford, C.W.; Baretta, A.; Fournier, J.; Waegell, B.
Helv. Chim. Acta 1970, 53, 1180-1184.
- “Chemical shifts of bromomethine protons of constrained α-bromocyclohexanones : An index of configuration and conformation”
Baretta, A.; Zahra, J.P.; Waegell, B.; Jefford, C.W.
Tetrahedron 1970, 26, 15-26.
- “Etude de quelques dérivés bromés de la tétraméthyl-2,2,6,6 tétrahydropyranone-4 par résonance magnétique nucléaire : Stéréochimie des couplages à longue distance”
Zahra, J.P.; Jefford, C.W.; Waegell, B.
Tetrahedron 1969, 25, 5087-5098.
- “The addition of bromofluorocarbene to norbornene”
Jefford, C.W.; Hill, D.T.
Tetrahedron Lett. 1969, 10, 1957-1960.
- “Stereochemistry of bicyclo[3.2.1]octane. XIX. Stereochemical requirements for proton-fluorine spin-spin coupling over five bonds”
Jefford, C.W.; Hill, D.T.; Ghosez, L.; Toppet, S.; Ramey, K.C.
J. Am. Chem. Soc. 1969, 91, 1532-1534.
- “Stereochemistry of bicyclo[3.2.1]octane. XVIII. Addition of monochlorocarbene to bicyclo[2.2.2]oct-2-ene, 1-methyl- and 2-methyl-2-norbornene”
Jefford, C.W.; Wojnarowski, W.
Tetrahedron 1969, 36, 2089-2097.
- “The reaction of 2-methylnorbornene-2 with N-bromosuccinimide”
Jefford, C.W.; Wojnarowski, W.
Tetrahedron Lett. 1968, 9, 3763-3766.
- “Steric course of the addition of monochloro-carbenoid to some bridged bicyclic olefins”
Jefford, C.W.; Wojnarowski, W.
Tetrahedron Lett. 1968, 9, 193-197.
- “The Stereochemistry of bicyclo[3.2.1]octane–XVI: Allylic reactivity of bicyclo[3.2.1]octene-2; reduction with metal hydrides”
Jefford, C.W.; Mahajan, S.N.; Gunsher, J.
Tetrahedron 1968, 24, 2921-2926.
- “The stereochemistry of bicyclo[3.2.1]octane–XVII: Long range internuclear spin interactions between protons in derivatives of bicyclo[3.2.1]octene-2”
Jefford, C.W.; Ramey, K.C.
Tetrahedron 1968, 24, 2927-2935.
- “Stereochemical consequences of the addition of chlorocarbenoid to some bridged bicyclic olefins”
Jefford, C.W.; Wojnarowski, W.
Tetrahedron Lett. 1968, 9, 199-202.
- “The 2-methylene-3-norbornyl cation”
Jefford, C.W.; Wojnarowski, W.
Chem. Commun. (London) 1968, 129-130.
- “Stereochemistry of bicyclo[3.2.1]octane. XV. Acetolysis of constrained cyclohexyl tosylates”
Jefford, C.W.; Hill, D.T.; Gunsher, J.
J. Am. Chem. Soc. 1967, 89, 6881-6884.
- “The stereochemistry of bicyclo[3.2.1]octane–XII: The photohalogenation of bicyclo[3.2.1]octene-2 derivatives”
Jeffford, C.W.; Yen, E.H.
Tetrahedron 1967, 23, 4549-4555.
- “The stereochemistry of bicyclo[3.2.1]octane–XI: The addition of monohalocarbene to norbornene”
Jefford, C.W.; Medary, R.T.
Tetrahedron 1967, 23, 4123-4129.
- “Entry to the bicyclo[4,2,1]nonane system”
Jefford, C.W.; Mahajan, S.N.; Medary, R.T.; Wojnarowski, W.; Waegell, B.; Ramey, K.C.
Chem. Commun. (London) 1967, 310-311.
- “Stereochemical consequences of the reaction of monohalocarbene with norbornene”
Jefford, C.W.; Yen, E.H.; Medary, R.
Tetrahedron Lett. 1966, 7, 6317-6321.
- “La photohalogénation du squelette du bicyclo(3.2.1.)octène-2”
Jefford, C.W.; Yen, E.H.
Tetrahedron Lett. 1966, 7, 4477-4480.
- “Long-range coupling between protons in derivatives of bicyclo[3.2.1]octane”
Waegell, B.; Jefford, C.W.
Spec. Publ. - Chem. Soc. 1966, 105-110.
- “The stereochemical consequences of the addition of chlorocarbene to norbornene”
Jefford, C.W.; Medary, R.
Tetrahedron Lett. 1966, 7, 2069-2075.
- “Conformations of the bicyclo[3,2,2]non-2-ene skeleton”
Jefford, C.W.; Mahajan, S.; Ramey, K.C.
Chem. Commun. (London) 1965, 616-617.
- “Multiple Long-Range Couplings between Protons in the Bicyclo[3.2.1]octene-2 Skeleton”
Jefford, C.W.; Gunsher, J.; Ramey, K.C.
J. Am. Chem. Soc. 1965, 87, 4384-4385.
- “Long-Range Interactions in Semidiones in the Bicyclo[3.1.1]heptane, Bicyclo[3.2.1]octane, Bicyclo-[3.2.2]nonane, and Bicyclo[3.3.1]nonane Systems”
Russell, G.A.; Chang, K.Y.; Jefford, C.W.
J. Am. Chem. Soc. 1965, 87, 4383-4384.
- “The acetolysis of constrained cyclohexyl tosylates”
Jefford, C.W.; Gunsher, J.; Waegell, B.
Tetrahedron Lett. 1965, 6, 3405-3411.
- “Allylic rearrangement of exo-1-methyl-3,4-dibromobicyclo[3.2.1]octene-2”
Jefford, C.W.; Mahajan, S.; Gunsher, J.; Waegell, B.
Tetrahedron Lett. 1965, 6, 2333-2340.
- “The Stereochemistry of the Bicyclo[3.2.1]octane System. IV. Some Long-Range Couplings of Vinyl and Allylic Protons”
Jefford, C.W.; Waegell, B.; Ramey, K.
J. Am. Chem. Soc. 1965, 87, 2191-2193.
- “The Stereochemistry of the Bicyclo[3.2.1]octane System. III. The Addition of Dihalocarbene to Bicyclic Olefins”
Jefford, C.W.; Mahajan, S.; Waslyn, J.; Waegell, B.
J. Am. Chem. Soc. 1965, 87, 2183-2190.
- “Interactions spin-spin nucleaires III Couplage spin-spin a “Longue Distance” 4JHH entre protons”
Rassat, A.; Jefford, C.W.; Lehn, J.M.; Waegell, B.
Tetrahedron Lett. 1964, 5, 233-243.
- “Cyclic ketones. XVI. The reflex effect. 5. Conformational studies in the bicyclo[3.2.1]octane series. B. Bromo derivatives of bicyclo[3.2.1]octan-3-one”
Waegell, B.; Jefford, C.W.
Bull. Soc. Chim. Fr. 1964, 844-854.
- “The bromination of bicyclo(3.2.1)octanone-3. An example of an α,α′-diaxial dibromocyclohexanone”
Jefford, C.W.; Waegell, B.
Tetrahedron Lett. 1963, 4, 1981-1986.
- “Bicyclo[3.2.1]octan-3-one”
Jefford, C.W.
Proc. Chem. Soc. 1963, 64.
- “New route to diazine mono-N-oxides”
Taylor, E.C.; Jefford, C.W.
Chem. Ind. 1963, 1559-1560.
- “The Rearrangement of 5-Nitroso-6-aminopyrimidines to s-Triazines”
Taylor, E.C.; Jefford, C.W.
J. Am. Chem. Soc. 1962, 84, 3744-3748.
- “The rearrangement of 5-nitroso-6-aminopyrimidines to s-triazines. New routes to N-heterocyclic N-oxides”
Jefford, C.W.
in Dissertation Abstracts; Princeton University, 1962; Vol. 23; p. 113.
- “A novel rearrangement of pyrimidines to s-triazines”
Taylor, E.C.; Jefford, C.W.; Cheng, C.C.
J. Am. Chem. Soc. 1961, 83, 1261-1262.
- “527. Addition reactions of heterocyclic compounds. Part III. 2 : 3-Benzacridine and some dienophils”
Acheson, R.M.; Jefford, C.W.
J. Chem. Soc. 1956, 2676-2679.
- “Some tautomeric acridines”
Acheson, R.M.; Burstall, M.L.; Jefford, C.W.; Sansom, B.F.
J. Chem. Soc. 1954, 3742-3746.