In living tissues, cells organize their movement in order to undergo large-scale restructuration events, such as tissue folding. These morphological changes are associated with a specific cell organization and active flows within tissues, and are essential for epithelial reshaping and renewal throughout organo- and morphogenesis, tissue regeneration and cancer metastasis.

My project studies the interplay between tissue reshaping and tissue mechanodynamics by preparing cell monolayers under physical constraints, which aim at inducing folds in localized regions.