Section de chimie et biochimie Section de chimie et biochimie

Publications 

  1. High-Speed Atomic Force Microscopy Highlights New Molecular Mechanism of Daptomycin Action
    Zuttion, F.; Colom, A.; Matile, S.; Farago, D.; Pompeo, F.; Kokavecz, J.; Galinier, A.; Sturgis, J.; Casuso, I.
    Nat. Commun. 2020, 11, 6312
  1. From Phenotypic Hit to Chemical Probe: Chemical Biology Approaches to Elucidate Small Molecule Action in Complex Biological Systems
    Pasquer, Q. T. L.; Tsakoumagkos, I. A.; Hoogendoorn, S.
    Molecules 2020, 25, 5702
  1. Pnictogen-Bonding Catalysis:  An Interactive Tool to Uncover Unorthodox Mechanisms in Polyether Cascade Cyclizations
    Paraja, M.; Gini, A.; Sakai, N.; Matile, S.
    Chem. Eur. J. 2020, 26, 15471-15475
  1. Preparation and structural characterization of [CpRu(1,10-phenanthroline)(CH3CN)][X] and precursor complexes (X= PF6, BArF, TRISPHAT-N)
    Achard, T.; Egger, L.; Tortoreto, C.; Guénée, L.; Lacour, J.
    Helv. Chim. Acta 2020, 103, e2000190
  1. The Structure of Molecular and Surface Platinum Sites Determined by DNP-SENS and Fast MAS 195Pt Solid-State NMR Spectroscopy
    Venkatesh, A.; Lund, A.; Rochlitz, L.; Jabbour, R.; Gordon, C. P.; Menzildjian, G.; Viger-Gravel, J.; Berruyer, P.; Gajan, D.; Copéret, C.; Lesage, A.; Rossini, A. J.
    J. Am. Chem. Soc. 2020, 142, 18936-18945
  1. Mechanosensitive Fluorescent Probes, Changing Color Like Lobsters During Cooking:  Cascade Switching Variations
    Kato, T.; Strakova, K.; García-Calvo, J.; Sakai, N.; Matile, S.
    Bull. Chem. Soc. Jpn. 2020, 93, 1401-1411
  1. Naphthalenediimides with Cyclic Oligochalcogenides in Their Core
    Shybeka, I.; Aster, A.; Cheng, Y.; Sakai, N.; Frontera, A.; Vauthey, E.; Matile, S.
    Chem. Eur. J. 2020, 26, 14059-14063
  1. Synthesis and properties of chiral fluorescent helicene-BODIPY conjugates
    Moneva Lorente, P.; Wallabregue, A.; Zinna, F.; Besnard, C.; Di Bari, L.; Lacour, J.
    Org. Biomol. Chem. 2020, 18, 7677-7684
  1. Access to Chiral Rigid Hemicyanine Fluorophores from Tröger Bases and α-Imino Carbenes
    Saleh, N.; Bosmani, A.; Besnard, C.; Bürgi, T.; Jacquemin, D.; Lacour, J.
    Org. Lett. 2020, 22, 7599-7603
  1. Synthesis, Resolution, Configurational Stability, and Properties of Cationic Functionalized [5]Helicenes
    Marinova, M.; Pascal, S.; Guénée, L.; Besnard, C.; Shivachev, B.; Kostova, K.; Villani, C.; Franzini, R.; Dimitrov, V.; Lacour, J.
    J. Org. Chem. 2020, 85, 11908-11923
  1. Identification of immunodominant linear epitopes from SARS-CoV-2 patient plasma
    Farrera-Soler, L.; Daguer, J.-P.; Barluenga, S.; Vadas, O.; Cohen, P.; Pagano, S.; Yerly, S.; Kaiser, L.; Vuilleumier, N.; Winssinger, N.
    PLoS One 2020, 15, e0238089
  1. Editorial
    Kündig, E. P.
    CHIMIA 2020, 74, 649
  1. Small Molecules Targeting the Hedgehog Pathway: From Phenotype to Mechanistic Understanding
    Hoogendoorn, S.
    CHIMIA 2020, 74, 652-658
  1. Ni-Catalyzed Regiodivergent and Stereoselective Hydroalkylation of Acyclic Branched Dienes with Unstabilized C(sp3) Nucleophiles
    Shao, W.; Besnard, C.; Guénée, L.; Mazet, C.
    J. Am. Chem. Soc. 2020, 142, 16486-16492
  1. Conserved Functions of Ether Lipids and Sphingolipids in the Early Secretory Pathway
    Jiménez-Rojo, N.; Leonetti, M. D.; Zoni, V.; Colom, A.; Feng, S.; Iyengar, N. R.; Matile, S.; Roux, A.; Vanni, S.; Weissman, J. S.; Riezman, H.
    Curr. Biol. 2020, 30, 3775-3787.e7
  1. Automated High-Content Imaging for Cellular Uptake, from the Schmuck Cation to the Latest Cyclic Oligochalcogenides
    Martinent, R.; López-Andarias, J.; Moreau, D.; Cheng, Y.; Sakai, N.; Matile, S.
    Beilstein J. Org. Chem. 2020, 16, 2007-2016
  1. Fluorescent small-molecule agonists as follicle-stimulating hormone receptor imaging tools
    Hoogendoorn, S.; van Puijvelde, G. H. M.; van der Marel, G. A.; van Koppen, C. J.; Timmers, C. M.; Overkleeft, H. S.
    RSC Chem. Biol. 2020, 1, 263-272
  1. Endosomal Membrane Tension Regulates ESCRT-III-Dependent Intra-Lumenal Vesicle Formation
    Mercier, V.; Larios, J.; Molinard, G.; Goujon, A.; Matile, S.; Gruenberg, J.; Roux, A.
    Nat. Cell Biol. 2020, 22, 947-959
  1. Access to Optically Active 7-Membered Rings by a 2-Step Synthetic Sequence: Cu-Catalyzed Stereoselective Cyclopropanation of Branched 1,3-Dienes/Rh-Catalyzed Stereoconvergent [5+2] Cycloaddition
    Garbo, M.; Besnard, C.; Guénée, L.; Mazet, C.
    ACS Catal. 2020, 10, 9604-9611
  1. Near-Infrared Electrochemiluminescence in Water through Regioselective Sulfonation of Diaza [4] and [6]helicene Dyes
    Li, H.; Duwald, R.; Pascal, S.; Voci, S.; Besnard, C.; Bosson, J.; Bouffier, L.; Lacour, J.; Sojic, N.
    Chem. Commun. 2020, 56, 9771-9774
  1. HaloFlippers:  A General Tool for the Fluorescence Imaging of Precisely Localized Membrane Tension Changes in Living Cells
    Straková, K.; López-Andarias, J.; Jiménez-Rojo, N.; Chambers, J. E.; Marciniak, S. J.; Riezman, H.; Sakai, N.; Matile, S.
    ACS Cent. Sci. 2020, 6, 1376-1385
  1. The RB596 antibody recognizes a linear epitope from the spike S protein from SARS-CoV-2
    Farrera-Soler, L.; Daguer, J.-P.; Barluenga, S.; Winssinger, N.
    Antib. Rep. 2020, 3, e232
  1. Tateshina: Swiss Inspiration!
    Kündig, E. P.
    Chem. Asian J. 2020, 15, 2545-2547
  1. Fluorescent Membrane Tension Probes for Super-Resolution Microscopy:  Combining Mechanosensitive Cascade Switching with Dynamic-Covalent Ketone Chemistry
    García-Calvo, J.; Maillard, J.; Fureraj, I.; Strakova, K.; Colom, A.; Mercier, V.; Roux, A.; Vauthey, E.; Sakai, N.; Fürstenberg, A.; Matile, S.
    J. Am. Chem. Soc. 2020, 142, 12034-12038
  1. Pnictogen-Bonding Catalysis:  Brevetoxin-Type Polyether Cyclizations
    Gini, A.; Paraja, M.; Galmés, B.; Besnard, C.; Poblador-Bahamonde, A. I.; Sakai, N.; Frontera, A.; Matile, S.
    Chem. Sci. 2020, 11, 7086-7091
  1. [n]Dendralenes as a Platform for Selective Catalysis: Ligand-Controlled Cu-Catalyzed Chemo-, Regio-, and Enantioselective Borylations
    Desfeux, C.; Besnard, C.; Mazet, C.
    Org. Lett. 2020, 22, 8181-8187
  1. Sense-and-release Logic-gated Molecular Network Responding to Dimeric Cell Surface Proteins
    Angerani, S.; Winssinger, N.
    J. Am. Chem. Soc. 2020, 142, 12333-12340
  1. Mapping Cell Membrane Organization and Dynamics Using Soft Nano-Imprint Lithography
    Sansen, T.; Sanchez Fuentes, D.; Rathar, R.; Colom, A.; El Alaoui, F.; Viaud, J.; Macchione, M.; de Rossi, S.; Matile, S.; Gaudin, R.; Bäcker, V.; Carretero-Genevrier, A.; Picas, L.
    ACS Appl. Mater. Interfaces 2020, 12, 29000-29012
  1. Twisting and Tilting of a Mechanosensitive Molecular Probe Detects Order in Membranes
    Licari, G.; Strakova, K.; Matile, S.; Tajkhorshid, E.
    Chem. Sci. 2020, 11, 5637-5649
  1. Chiroptical Detection of a Model Ruthenium Dye in Water by Circularly Polarized-Electrochemiluminescence
    Voci, S.; Zinna, F.; Arrico, L.; Grass, S.; Bouffier, L.; Lacour, J.; Di Bari, L.; Sojic, N.
    Chem. Commun. 2020, 56, 5989-5992
  1. Empowering Global Chemical Biology at the Dawn of the New Decade
    Hoogendoorn, S.; Aye, Y.
    ACS Chem. Biol. 2020, 15, 1287-1291
  1. Peptide Stapling with Anion-π Catalysts
    Pham, A.-T.; Matile, S.
    Chem. Asian J. 2020, 15, 1562-1566
  1. Self-Enhanced Multicolor Electrochemiluminescence by Competitive Electron-transfer Processes
    Voci, S.; Duwald, R.; Grass, S.; Hayne, D. J.; Bouffier, L.; Francis, P. S.; Lacour, J.; Sojic, N.
    Chem. Sci. 2020, 11, 4508-4515
  1. Kilian Muñiz (1970-2020)
    Streuff, J.; Echavarren, A. M.; González, J. M.; Oestreich, M.; Gansäuer, A.; Barluenga, S.; Winssinger, N.
    Angew. Chem. Int. Ed. 2020, 59, 7648
  1. PNA-Based Dynamic Combinatorial Libraries (PDCL) and screening of lectins
    Farrera-Soler, L.; Daguer, J.-P.; Raunft, P.; Barluenga, S.; Imberty, A.; Winssinger, N.
    Bioorg. Med. Chem. 2020, 28, 115458
  1. A Catalytic Dual Isomerization/Allylboration Sequence for the Stereoselective Construction of Congested Secondary Homoallylic Alcohols
    Liu, Y.; Mazet, C.
    J. Org. Chem. 2020, 85, 5638-5650
  1. Enhanced SNP-sensing using DNA-templated reactions through confined hybridization of minimal substrates (CHOMS)
    Kim, K. T.; Winssinger, N.
    Chem. Sci. 2020, 11, 4150-4157
  1. Polyether Natural Product Inspired Cascade Cyclizations: Autocatalysis on π-Acidic Aromatic Surfaces
    Paraja, M.; Hao, X.; Matile, S.
    Angew. Chem. Int. Ed. 2020, 59, 15093-15097
  1. From reactive carbenes to chiral polyether macrocycles in two steps – synthesis and applications made easy?
    Homberg, A.; Lacour, J.
    Chem. Sci. 2020, 11, 6362-6369
  1. Smartphone DNA or RNA-Sensing Using Semisynthetic Luciferase-Based Logic Device
    Chang, D.; Kim, K. T.; Lindberg, E.; Winssinger, N.
    ACS Sens. 2020, 5, 807-813
  1. Cell-Penetrating Streptavidin:  A General Tool for Bifunctional Delivery with Spatiotemporal Control, Mediated by Transport Systems such as Adaptive Benzopolysulfane Networks
    López-Andarias, J.; Saarbach, J.; Moreau, D.; Cheng, Y.; Derivery, E.; Laurent, Q.; González-Gaitán, M.; Winssinger, N.; Sakai, N.; Matile, S.
    J. Am. Chem. Soc. 2020, 142, 4784-4792
  1. Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch9
    Plank, M.; Perepelkina, M.; Müller, M.; Vaga, S.; Zou, X.; Bourgoint, C.; Berti, M.; Saarbach, J.; Haesendonckx, S.; Winssinger, N.; Aebersold, R.; Loewith, R.
    Mol. Cell. Proteomics 2020, 19, 655-671
  1. PNA-Encoded Synthesis (PES) and DNA Display of Small Molecule Libraries
    Saarbach, J.; Barluenga, S.; Winssinger, N.
    in Peptide Nucleic Acids; Nielsen, P. (Ed.)Methods in Molecular Biology, vol. 2105; Humana: New York, NY, 2020; Chapter 7; p. 119-139
  1. Primary Anion-π Catalysis of Epoxide-Opening Ether Cyclizations into Rings of Different Sizes:  Access to New Reactivity
    Paraja, M.; Matile, S.
    Angew. Chem. Int. Ed. 2020, 59, 6273-6277
  1. Synthesis, characterization, catalytic and biological application of half-sandwich ruthenium complexes bearing hemilabile (κ2-C,S )-thioether-functionalised NHC ligands
    Chen, W.; Egly, J.; Poblador-Bahamonde, A. I.; Maisse-Francois, A.; Bellemin-Laponnaz, S.; Achard, T.
    Dalton Trans. 2020, 49, 3243-3252
  1. Caprin-1 Promotes Cellular Uptake of Nucleic Acids with Backbone and Sequence Discrimination
    Galli, V.; Sadhu, K. K.; Masi, D.; Saarbach, J.; Roux, A.; Winssinger, N.
    Helv. Chim. Acta 2020, 103, e1900255
  1. Enantiopure encaged Verkade's superbases: Synthesis, chiroptical properties, and use as chiral derivatizing agent
    Yang, J.; Chatelet, B.; Hérault, D.; Dufaud, V.; Robert, V.; Grass, S.; Lacour, J.; Vanthuyne, N.; Jean, M.; Albalat, M.; Dutasta, J.-P.; Martinez, A.
    Chirality 2020, 32, 139-146
  1. Mechanosensitive Membrane Probes:  Push-Pull Papillons
    Humeniuk, H. V.; Licari, G.; Vauthey, E.; Sakai, N.; Matile, S.
    Supramol. Chem. 2020, 33, 106-111
  1. Direct Access to Chiral Secondary Amides by Copper-Catalyzed Borylative Carboxamidation of Vinylarenes with Isocyanates
    Fiorito, D.; Liu, Y.; Besnard, C.; Mazet, C.
    J. Am. Chem. Soc. 2020, 142, 623-632
  1. Palmitate and Oleate Modify Membrane Fluidity and Kinase Activities of INS-1E ß-Cells Alongside Altered Metabolism-Secretion Coupling
    Oberhauser, L.; Granziera, S.; Colom, A.; Goujon, A.; Lavallard, V.; Matile, S.; Roux, A.; Brun, T.; Maechler, P.
    Biochim. Biophys. Acta, Mol. Cell Biol. Lipids 2020, 1867, 118619
  1. Photo-induced thiol–ene reactions for late-stage functionalization of unsaturated polyether macrocycles: regio and diastereoselective access to macrocyclic dithiol derivatives
    Brun, E.; Zhang, K.-F.; Guénée, L.; Lacour, J.
    Org. Biomol. Chem. 2020, 18, 250-254
  1. Merging polyacenes and cationic helicenes: from weak to intense chiroptical properties in the far red region
    Duwald, R.; Bosson, J.; Pascal, S.; Grass, S.; Zinna, F.; Besnard, C.; Di Bari, L.; Jacquemin, D.; Lacour, J.
    Chem. Sci. 2020, 11, 1165-1169
  1. Circularly polarized luminescence from intramolecular excimers
    Zinna, F.; Brun, E.; Homberg, A.; Lacour, J.
    in Circularly Polarized Luminescence of Isolated Small Organic Molecules; Mori, T. (Ed.) Springer: Singapore, 2020; Chapter 12; p. 273-292
  1. Small-molecule modulators of the ATPase VCP/p97 affect specific p97 cellular functions
    Figuerola-Conchas, A.; Saarbach, J.; Daguer, J.-P.; Cieren, A.; Barluenga, S.; Winssinger, N.; Gotta, M.
    ACS Chem. Biol. 2020, 15, 243-253
  1. Methyl Scanning for Mechanochemical Chalcogen-Bonding Cascade Switches
    Zhang, X.; Sakai, N.; Matile, S.
    ChemistryOpen 2020, 9, 18-22
  1. Untying the Photophysics of Quinolinium-Based Molecular Knots and Links
    Caprice, K.; Aster, A.; Cougnon, F. B. L.; Kumpulainen, T.
    Chem. Eur. J. 2020, 26, 1576-1587
  1. Probing for Thiol-Mediated Uptake into Bacteria
    Laurent, Q.; Berthet, M.; Cheng, Y.; Sakai, N.; Barluenga, S.; Winssinger, N.; Matile, S.
    ChemBioChem 2020, 21, 69-73
  1. Everything you wanted to know about phase and reference frequency in one- and two-dimensional NMR Spectroscopy
    Sheberstov, K. F.; Guardiola Sistare, E.; Jeannerat, D.
    Magn. Reson. Chem. 2020, 58, 376-389
  1. SAN plot: a Graphical representation of the signal, noise and artifacts content of spectra
    Sheberstov, K.; Sistaré Guardiola, E.; Pupier, M.; Jeannerat, D.
    Magn. Reson. Chem. 2020, 58, 466-472