Formateurs

GROUPE LOEWITH

LABORATORY OF PROF. ROBBIE LOEWITH

 

Our lab is interested in how cell growth is regulated via two protein complexes, TOR-complex 1 and 2, in response to nutrient levels and stresses. Using yeast as a model organism, we aim to:

- identify the molecular regulators upstream of the TOR complexes, primarily by using unbiased genetic screens (a traditional strong suit of yeast).

- identify new small-molecule inhibitors of the TOR complexes using state-of-the-art high-throughput screening. 

- identify the effectors downstream of the TOR complexes by determining cellular responses after its inhibition via mass spectrometry and biochemical methods.

- determine the atomic structures of the TOR complexes, upstream regulators and downstream effectors by electron microscopy and X-ray crystallography.

 

Loewith1.pngLoewith2.png

 

 

UNIGE.png

UFA.png

ADRESSE

University of Geneva
Department of Molecular Biology, Sc3 2045b
30, quai Ernest-Ansermet
CH-1211, Geneva 4, Switzerland

 

CONTACT

Michael Plank, PostDoc

Michael.Plank@unige.ch

Robbie Loewith, Principal Investigator

Robbie.Loewith(at)unige.ch