FrontiersInBiomedicine

Le cycle de séminaires des Frontiers in Biomedicine (anciennement "Frontiers in Biology"), initié par la Faculté de médecine en 2003 par les départements de la Section de médecine fondamentale, a pour but d’établir un pont entre médecine et biologie à travers une série de 8 à 10 conférences annuelles.
Des intervenants de renommée mondiale, actifs dans le domaine des sciences de la médecine, sont invités à présenter leur travail à un large public scientifique et médical. Les conférences sont données en anglais.


The Frontiers In Biomedicine (initially "Frontiers in Biology") lecture series was initiated in 2003 at Geneva University’s Faculty of Medicine. The series aims to bridge the gap between biology and medicine through a cycle of eight to ten seminars per year. World-class guest speakers from all domains of the basic medical sciences are invited to present broadly accessible lectures to a non-specialist scientific audience. In English.

Thursdays, 12.30 - 13.30
CMU - C150

Next Conference:

Jeudi 23 mars 2017
12h30, CMU - C150
 
Prof. Anthony HYMAN
Director and Group Leader
Max Planck Institute of Molecular Cell Biology and Genetics

Photo_Hyman_WEB_by_Tristan_Vostry.jpg

«Like oil and water: phase separation in the cytoplasm and implications for neurodegeneration»

Cells organize many of their biochemical reactions by formation and dissolution of non-membrane-bound compartments. Recent experiments show that a common mechanism for such biochemical organization is phase separation of unstructured proteins to form liquid-like compartments.  These liquid-like compartments can be described by principles elucidated from condensed-matter physics and are therefore termed biomolecular condensates.  I will discuss the relationship between the formation of liquid like compartments, and the onset of aggregated-protein pathology that is commonly observed in neurodegenerative diseases.

 

"Anthony Hyman is an outstanding cell biologist and an excellent and inspiring speaker. 

In addition to the many findings in the field of cell division, his original approach has led to the discovery that cells can organize biochemical reactions in liquid-like membrane-free compartments that separate from the rest of the cytoplasm like oil separates from water. 

This discovery has important implications for the understanding of human disease since with age or metabolic changes liquid-like compartments can convert into more solid structures found in neurodegenerative disorders."

Monica GOTTA, Host
Département de physiologie cellulaire et métabolisme, Faculté de médecine UNIGE

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