Faculté de médecine Faculté de médecine

Publications

TSE Labmaster (Acquired in 2008):

2017

  • Brenachot X, Ramadori G, Ioris RM, Veyrat-Durebex C, Altirriba J, Aras E, Ljubicic S, Kohno D, Fabbiano S, Clement S, Goossens N, Trajkovski M, Harroch S, Negro F, Coppari R. Hepatic protein tyrosine phosphatase receptor gamma links obesity-induced inflammation to insulin resistance. Nat Commun. 2017 Nov 28;8(1):1820.
  • Brun J, Berthou F, Trajkovski M, Maechler P, Foti M, Bonnet N. Bone Regulates Browning and Energy Metabolism Through Mature Osteoblast/Osteocyte PPARγ Expression. Diabetes. 2017 Jul 7.

2016

  • Fabbiano S, Suárez-Zamorano N, Rigo D, Veyrat-Durebex C, Stevanovic Dokic A, Colin DJ, Trajkovski M. Caloric Restriction Leads to Browning of White Adipose Tissue through Type 2 ImmuneSignaling. Cell Metab. 2016 Sep 13;24(3):434-46.

2015

  • Poher AL, Veyrat-Durebex C, Altirriba J3, Montet X, J Colin D, Caillon A, Lyautey J, Rohner-Jeanrenaud F. Ectopic UCP1 overexpression in white adipose tissue improves insulin sensitivity in Lou/C rats, a model of obesity resistance.Diabetes. 2015 Jul 29. pii: db150210.
  • Peyrou M, Bourgoin L, Poher AL, Altirriba J, Maeder C, Caillon A, Fournier M, Montet X, Rohner-Jeanrenaud F, Foti M. Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in mice. J Hepatol. 2015;62(2):421-9.

2014

  • Somm E, Guérardel A, Maouche K, Toulotte A, Veyrat-Durebex C, Rohner-Jeanrenaud F, Maskos U, Hüppi PS, Schwitzgebel VM. Concomitant alpha7 and beta2 nicotinic AChR subunit deficiency leads to impaired energy homeostasis and increased physical activity in mice. Mol Genet Metab. 2014;112(1):64-72.

2013

  • Veyrat-Durebex C, Poher AL, Caillon A, Somm E, Vallet P, Charnay Y, Rohner-Jeanrenaud F.  Improved leptin sensitivity as a potential candidate responsible for the spontaneous food restriction of the Lou/C rat. PLoS One. 2013;8(9):e73452.
  • Somm E, Bonnet N, Zizzari P, Tolle V, Toulotte A, Jones R, Epelbaum J, Martinez A, Hüppi PS, Aubert ML. Comparative inhibition of the GH/IGF-I axis obtained with either the targeted secretion inhibitor SXN101959 or the somatostatin analog octreotide in growing male rats. Endocrinology. 2013;154(11):4237-48.

2012

  • Veyrat-Durebex C, Deblon N, Caillon A, Andrew R, Altirriba J, Odermatt A, Rohner-Jeanrenaud F. Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue. PLoS One. 2012;7(3):e34002.
  • Deblon N, Bourgoin L, Veyrat-Durebex C, Peyrou M, Vinciguerra M, Caillon A, Maeder C, Fournier M, Montet X, Rohner-Jeanrenaud F, Foti M. Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats. Br J Pharmacol. 2012; 165(7):2325-40.
  • Li Y, Mouche S, Sajic T, Veyrat-Durebex C, Supale R, Pierroz D, Ferrari S, Negro F, Hasler U, Feraille E, Moll S, Meda P, Deffert C, Montet X, Krause KH, Szanto I. Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity. Int J Obes (Lond). 2012;36(12):1503-13.
  • Zimmermann C, Cederroth CR, Bourgoin L, Foti M, Nef S. Prevention of diabetes in db/db mice by dietary soy is independent of isoflavone levels. Endocrinology. 2012;153(11):5200-11.
  • Batista TM, Alonso-Magdalena P, Vieira E, Amaral ME, Cederroth CR, Nef S, Quesada I, Carneiro EM, Nadal A. Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice. PLoS One. 2012;7(3):e33814

 

2011

  • Veyrat-Durebex C, Poher AL, Caillon A, Montet X, Rohner-Jeanrenaud F. Alterations in lipid metabolism and thermogenesis with emergence of brown adipocytes in white adipose tissue in diet-induced obesity-resistant Lou/C rats. Am J Physiol Endocrinol Metab. 2011; 300(6):E1146-57.
  • Deblon N, Veyrat-Durebex C, Bourgoin L, Caillon A, Bussier AL, Petrosino S, Piscitelli F, Legros JJ, Geenen V, Foti M, Wahli W, Di Marzo V, Rohner-Jeanrenaud F. Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats. PLoS One. 2011; 6(9):e25565.
  • Disse E, Bussier AL, Deblon N, Pfluger PT, Tschöp MH, Laville M, Rohner-Jeanrenaud F. Systemic ghrelin and reward: effect of cholinergic blockade. Physiol Behav. 2011; 102(5):481-4.

2010

  • Disse E, Bussier AL, Veyrat-Durebex C, Deblon N, Pfluger PT, Tschöp MH, Laville M, Rohner-Jeanrenaud F. Peripheral ghrelin enhances sweet taste food consumption and preference, regardless of its caloric content. Physiol Behav. 2010; 101(2):277-81.
  • Serre-Beinier V, Toso C, Morel P, Gonelle-Gispert C, Veyrat-Durebex C, Rohner-Jeanrenaud F, Calandra T, Roger T, James RW, Montet X, Bühler L, Bosco D, Berney T. Macrophage migration inhibitory factor deficiency leads to age-dependent impairment of glucose homeostasis in mice. J Endocrinol. 2010; 206(3):297-306.

2009

  • Nogueiras R, Pérez-Tilve D, Veyrat-Durebex C, Morgan DA, Varela L, Haynes WG, Patterson JT, Disse E, Pfluger PT, López M, Woods SC, DiMarchi R, Diéguez C, Rahmouni K, Rohner-Jeanrenaud F, Tschöp MH. Direct control of peripheral lipid deposition by CNS GLP-1 receptor signaling is mediated by the sympathetic nervous system and blunted in diet-induced obesity. J Neurosci. 2009; 29(18):5916-25.

2008

  • Somm E, Schwitzgebel VM, Vauthay DM, Camm EJ, Chen CY, Giacobino JP, Sizonenko SV, Aubert ML, Hüppi PS. Prenatal nicotine exposure alters early pancreatic islet and adipose tissue development with consequences on the control of body weight and glucose metabolism later in life. Endocrinology. 2008; 149(12):6289-99.

2006

  • Theander-Carrillo C, Wiedmer P, Cettour-Rose P, Nogueiras R, Perez-Tilve D, Pfluger P, Castaneda TR, Muzzin P, Schurmann A, Szanto I, Tschop MH, Rohner-Jeanrenaud F. Ghrelin action in the brain controls adipocyte metabolism. J Clin Invest. 2006 Jul;116(7):1983-93.
  • Nogueiras R, Pfluger P, Tovar S, Myrtha A, Mitchell S, Morris A, Perez-Tilve D, Vazquez MJ, Wiedmer P, Castaneda TR, Dimarchi R, Tschop M, Schurmann A, Joost HG, Williams LM, Langhans W, Dieguez C. Effects of obestatin on energy balance and growth hormone secretion in rodents. Endocrinology. 2006 Sep 28;

Glucose / lipids homeostasis

Clamp

2019

  • Aras E, Ramadori G, Kinouchi K, Liu Y, Ioris RM, Brenachot X, Ljubicic S, Veyrat-Durebex C, Mannucci S, Galié M, Baldi P, Sassone-Corsi P, Coppari R. Light Entrains Diurnal Changes in Insulin Sensitivity of Skeletal Muscle via Ventromedial Hypothalamic Neurons. Cell Rep. 2019 May 21

2018

  • Fabbiano S, Suárez-Zamorano N, Chevalier C, Lazarević V, Kieser S, Rigo D, Leo S, Veyrat-Durebex C, Gaïa N, Maresca M, Merkler D, Gomez de Agüero M, Macpherson A, Schrenzel J, Trajkovski M. Functional Gut Microbiota Remodeling Contributes to the Caloric Restriction-Induced Metabolic Improvements. Cell Metab. 2018 Aug 24

2017

  • Brenachot X, Ramadori G, Ioris RM, Veyrat-Durebex C, Altirriba J, Aras E, Ljubicic S, Kohno D, Fabbiano S, Clement S, Goossens N, Trajkovski M, Harroch S, Negro F, Coppari R. Hepatic protein tyrosine phosphatase receptor gamma links obesity-induced inflammation to insulin resistance. Nat Commun. 2017 Nov 28;8(1):1820.

2016 

  • Fabbiano S, Suárez-Zamorano N, Rigo D, Veyrat-Durebex C, Stevanovic Dokic A, Colin DJ, Trajkovski M. Caloric Restriction Leads to Browning of White Adipose Tissue through Type 2 Immune Signaling. Cell Metab. 2016 Sep 13;24(3):434-446. doi: 10.1016/j.cmet.2016.07.023. Epub 2016 Aug 25 

2015

  • Chevalier C, Stojanović O, Colin DJ, Suarez-Zamorano N, Tarallo V, Veyrat-Durebex C, Rigo D, Fabbiano S, Stevanović A, Hagemann S, Montet X, Seimbille Y, Zamboni N, Hapfelmeier S, Trajkovski M. Gut Microbiota Orchestrates Energy Homeostasis during Cold. Cell. 2015 Dec 3;163(6):1360-74.

  • Anderson JG, Ramadori G, Ioris RM, Galiè M, Berglund ED, Coate KC, Fujikawa T, Pucciarelli S, Moreschini B, Amici A, Andreani C, Coppari R. Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6. Mol Metab. 2015 Sep 25;4(11):846-856.

  • Suárez-Zamorano N, Fabbiano S, Chevalier C, Stojanović O, Colin DJ, Stevanović A, Veyrat-Durebex C, Tarallo V, Rigo D, Germain S, Ilievska M, Montet X, Seimbille Y, Hapfelmeier S, Trajkovski M. Microbiota depletion promotes browning of white adipose tissue and reduces obesity. Nat Med. 2015 Nov 16.
  • Poher AL, Veyrat-Durebex C, Altirriba J, Montet X, Colin D.J, Caillon A, Lyautey J and Rohner-Jeanrenaud F. Ectopic UCP1 overexpression in white adipose tissue improves insulin sensitivity in Lou/C rats, a model of obesity resistance. Diabetes 2015

2013

  • Marcelino H, Veyrat-Durebex C, Summermatter S, et al.  A role for adipose tissue de-novo lipogenesis in glucose homeostasis during catch-up growth: a Randle cycle favouring fat storage.  Diabetes 2013 Feb;62(2):362-72. (http://www.ncbi.nlm.nih.gov/pubmed/22961086)

2012

  • Deblon N, Bourgoin L,Veyrat-Durebex C, Peyrou M, Vinciguerra M, Caillon A, Maeder C, Fournier M, Montet X, Rohner-Jeanrenaud F and Foti M.  Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats. British Journal of Pharmacology, 2012 Apr;165(7):2325-40.
  • Lockie SH, Heppner KM, Chaudhary N, Chabenne JR, Morgan DA, Veyrat-Durebex C, et al.  Direct control of brown adipose tissue thermogenesis by central nervous system Glucagon-Like Peptide-1 receptor signaling. Diabetes 2012 Nov;61(11):2753-62 (http://www.ncbi.nlm.nih.gov/pubmed/22933116)

2011

  • Deblon N, Veyrat-Durebex C, Bourgoin L, Caillon A, Bussier AL, Petrosino S, Piscitelli F, Legros JJ, Geenen V, Foti M, Wahli W, Di Marzo V, Rohner-Jeanrenaud F.  Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats. PlosOne 2011, 6(9):e25565.

 2010

  • Serre-Beinier V, Toso C, Morel P, Gonelle-Gispert C, Veyrat-Durebex C, Rohner-Jeanrenaud F, Calandra T, Roger T, James RW, Montet X, Bühler L, Bosco D and Berney T.  Macrophage migration inhibitory factor-deficiency leads to age-dependent impairment of glucose homeostasis in mice. J Endocrinol Sep;206(3):297-306, 2010.

 2009

  • Veyrat-Durebex C, Montet X, Vinciguerra M, Gjinovci A, Meda P, Foti M and Rohner-Jeanrenaud F.  The Lou/C rat: A model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue.  Am J Physiol, Endocrinol Metab, May;296(5):E1120-32, 2009.

 2008

  • Nogueiras R*, Veyrat-Durebex C*, Klein M, Tschöp J, Caldwell C, Reizes O, Woods SC, Liposits Z, Fekete C, Rohner-Jeanrenaud F and Tschöp MH.  Peripheral, but not central, CB1 antagonism provides food intake independent metabolic benefits in diet-induced obese rats. *These authors have contributed equally to this work. Diabetes, Nov;57(11):2977-91, 2008.

 2007

  • Nogueiras R, Wiedmer P, Perez-Tilve D, Veyrat-Durebex C, Keogh JM, Sutton GM, Pfluger P, Castaneda TR, Neschen S, Hofmann SM, Howles PN, Morgan DA, Benoit SC, Szanto I, Schrott B, Schürmann A, Joost H, Hammond C, Hui DY, Woods SC, Rhamounhi K, Butler AA, Farooqi S, O’Rahilly S, Rohner-Jeanrenaud F and Tschöp MH.  The central nervous melanocortin system directly controls peripheral lipid metabolism. J Clin Invest, Nov 117(11), 3475-3488, 2007. IF 16.92

 

 Echo MRI-700 (Acquired in 2010)

 

2017

 

  • Poher AL, Arsenijevic D, Asrih M, Dulloo AG, Jornayvaz FR, Rohner-Jeanrenaud F, Veyrat-Durebex C. Preserving of Postnatal Leptin Signaling in Obesity-Resistant Lou/C Rats following a Perinatal High-Fat Diet. PLoS One. 2016 Sep 12;11(9):e0162517.

 

2015

  • Peyrou M, Bourgoin L, Poher AL, Altirriba J, Maeder C, Caillon A, Fournier M, Montet X, Rohner-Jeanrenaud F, Foti M. Hepatic PTEN deficiency improves muscle insulin sensitivity and decreases adiposity in mice. J Hepatol. 2015;62(2):421-9.

2014

  • Altirriba J, Poher AL, Caillon A, Arsenijevic D, Veyrat-Durebex C, Lyautey J, Dulloo A, Rohner-Jeanrenaud F. Divergent effects of oxytocin treatment of obese diabetic mice on adiposity and diabetes. Endocrinology. 2014;155(11):4189-201.

2013

  • Veyrat-Durebex C, Poher AL, Caillon A, Somm E, Vallet P, Charnay Y, Rohner-Jeanrenaud F.  Improved leptin sensitivity as a potential candidate responsible for the spontaneous food restriction of the Lou/C rat. PLoS One. 2013;8(9):e73452.

2012

  • Veyrat-Durebex C, Deblon N, Caillon A, Andrew R, Altirriba J, Odermatt A, Rohner-Jeanrenaud F. Central glucocorticoid administration promotes weight gain and increased 11β-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue. PLoS One. 2012; 7(3):e34002.
  • Deblon N, Bourgoin L, Veyrat-Durebex C, Peyrou M, Vinciguerra M, Caillon A, Maeder C, Fournier M, Montet X, Rohner-Jeanrenaud F, Foti M. Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats. Br J Pharmacol. 2012; 165(7):2325-40.

 

2011

  • Deblon N, Veyrat-Durebex C, Bourgoin L, Caillon A, Bussier AL, Petrosino S, Piscitelli F, Legros JJ, Geenen V, Foti M, Wahli W, Di Marzo V, Rohner-Jeanrenaud F. Mechanisms of the anti-obesity effects of oxytocin in diet-induced obese rats. PLoS One. 2011; 6(9):e25565.
  • Veyrat-Durebex C, Poher AL, Caillon A, Montet X, Rohner-Jeanrenaud F. Alterations in lipid metabolism and thermogenesis with emergence of brown adipocytes in white adipose tissue in diet-induced obesity-resistant Lou/C rats. Am J Physiol Endocrinol Metab. 2011; 300(6):E1146-57.