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New insights into microbial diversity related to mercury bioconversion brought by high-throughput omics

Venue : Fondation “Les Bois Chamblard” – Buchillon, Switzerland


Recent studies identified the hgcAB gene cluster in microorganisms with the ability to methylate HgII and revealed a wider range of species and environmental conditions producing MMHg than previously thought. However, most studies were conducted on DNA so far and, as such, do not reflect the activity of the protein, but only the possibility that a strain may methylate HgII.

HgII methylation is a riddle in which the efficiency of the biological HgII methylation appears to depend on many bio-physico-chemical processes and parameters. Therefore, a better understanding of the complexity of microbial communities is essential to describe all the metabolic processes that can directly or indirectly affect HgII methylation.

This workshop aims to bring together scientists involved or interested in discussing the latest results, constraints and limitations of using advanced high-throughput biological analysis, i.e. metagenomics, metatranscriptomics and metaproteomics to identify microbial structure and functionality, to enable a better mechanistic understanding of biological processes related to Hg methylation.

This workshop will be structured in two parts, the morning devoted to presentations of current knowledge on the subject, and the afternoon to group discussions on specific points.

 The workshop is free, lunch is included, however participants are requested to register by sending an email to Jean-Luc Loizeau

May 19, 2022
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