Oliver Soehnlein
Oliver Soehnlein is Professor of Regulatory Mechanisms of Inflammation and Director of the Institute of Experimental Pathology at the Universitiy of Münster, Germany. He received his M.D. in 2004 from the Friedrich-Alexander University of Erlangen, Germany, and his Ph.D. from the Karolinska Institutet, Sweden. Oliver Soehnlein’s research focuses on understanding the role of myeloid cells in vascular inflammation. Based on this understanding he aims at designing tailored therapeutic approaches.
He also holds a Professorship at the Department of Physiology and Pharmacology at the Karolinska Institute in Stockholm, Sweden.
Read more here: https://dzhk.de/forschung/forschungsgruppen/dzhk-professuren/oliversoehnlein/
PRESENTATION SUMMARY
Neutrophils in chronic inflammation: from physiology to intervention
Neutrophils have traditionally been viewed as bystanders or biomarkers of cardiovascular disease. However, studies in the past decade have demonstrated the important functions of neutrophils during cardiovascular inflammation and repair. In my talk, I will highlight the influence of traditional and novel cardiovascular risk factors on neutrophil production and function. I will then discuss our studies on the contribution of neutrophils to the different stages of atherosclerosis with specific emphasize on plaque destabilization. Finally, I will emphasize how detailed knowledge of neutrophil functions in cardiovascular homeostasis and disease can be used to generate therapeutic strategies to target neutrophil numbers, functional status and effector mechanisms.