GCIR Seminar on Graft-versus-host disease 21 Nov 2025
Friday, 21 November 2025
14h30 - 16h00
Renold Auditorium, CMU
The GCIR Scientific Seminars are designed for researchers and biomedical students and focus on both clinical and fundamental research related to infection, immunology, and inflammation.
We are pleased to invite you to our upcoming seminar dedicated to Graft-versus-Host Disease (GvHD), hosted by Prof. Jean Villard and Prof. Federico Simonetta, members of the GCIR.
This seminar will feature distinguished speakers presenting recent advances in the understanding and management of GvHD, including genomics, molecular imaging, and microbiome modulation.
Program Overview
- Prof. Florent Malard, Sorbonne Université and Hôpital Saint-Antoine, Paris, France
Microbiome modulation in patients undergoing allogeneic hematopoietic cell transplantation - Prof. Simona Pagliuca, CHRU de Nancy, Université de Lorraine, France
Determinants of alloreactivity in allogeneic hematopoietic stem cell transplantation for myeloid neoplasms: graft-versus-leukemia effect versus graft-versus-host disease - Prof. Federico Simonetta, GCIR, UNIGE Faculty of Medicine
Molecular imaging of graft-versus-host disease - Dr Chiara Bernardi, (Short talk) Simonetta Lab, GCIR, UNIGE Faculty of Medicine
Influence of Time-of-Day of Graft Infusion on Allogeneic Hematopoietic Stem Cell Transplantation Outcomes
We are grateful to our seminar sponsors, MesenFlow Technologies, Light Chain Bioscience and AMAL Therapeutics, for their invaluable support.
Join us for an engaging afternoon of scientific exchange and discussion on the latest research in GvHD.
SPEAKERS BIOGRAPHIES
Florent Malard, MD, PhD, studied medicine at the University of Nantes, France and obtained his PhD degree at Sorbonne Université in Paris, France, followed by a postdoctoral fellowship at the Memorial Sloan Kettering Cancer Centre, New York, USA. He is now appointed as a Professor of Haematology at Sorbonne Université and Saint-Antoine Hospital, Paris, France. His research works focused on allogeneic hematopoietic cell transplantation, immunology, microbiota and multiple myeloma. He has published over 200 publications on these topics.
Simona Pagliuca, MD, PhD, is a Professor of Immunology and haematologist at the University of Lorraine and Nancy University Hospital (France). Her clinical and research work centres on bone marrow failure syndromes, allogeneic hematopoietic stem cell transplantation, and cellular therapies. Trained at the University of Naples Federico II, she served as a senior physician in the Haematology and Transplant Unit at Hôpital Saint-Louis, Paris (2016–2019). She subsequently completed two years of protected research in the Maciejewski Laboratory at the Cleveland Clinic (Ohio, USA), developing expertise in immunogenetics and computational immunology applied to haematology. She earned a PhD in immuno-haematology from the University of Paris in 2021. Her current program investigates immune dysregulation in hematologic diseases, leveraging immunogenetics, T-cell receptor repertoire profiling, and immune monitoring in transplant and CAR-T recipients. She is an active member of the European Blood and Marrow Transplant Group (EBMT) and, in particular, of the Severe Aplastic Anaemia and Cellular Therapy & Immunobiology Working Parties; of the American and European Society of Haematology as well as of the Francophone Society of Bone Marrow Transplantation and Cellular Therapy (SFGM-TC)
GCIR member Dr Federico Simonetta is currently a Senior Clinical Associate within the Division of Haematology, Department of Oncology, HUG. After his MD from the University of Genoa, Italy, he obtained an MSc in Immunology from the Pasteur Institute/University of Paris-VII and a PhD in Immunology from the University of Paris-Sud. He then did his postgraduate training in Internal Medicine and Haematology at HUG. Between 2016 and 2019, he was a postdoctoral fellow in the lab of Pr. RS Negrin at Stanford University. He is a member of the Working group for Cellular Therapies of the SAKK and the SBST and of the Swiss Board on Multiple Myeloma CAR T cells. He is co-chair of the Immune monitoring subcommittee of the Cellular Therapy & Immunobiology Working Party (CTIWP) of the European Society for Blood and Marrow Transplantation (EBMT).
Dr Chiara Bernardi is a physician-scientist specialised in haematology and immunology. She obtained her medical degree from the University of Padua, Italy, and earned her PhD in Immunology from the University of Strasbourg in 2020, where she investigated the role of Ikaros in regulating GM-CSF expression and CD4⁺ T-cell pathogenicity. She obtained her FMH specialisation in Haematology in 2024.
She currently serves as Chief Resident in the Division of Haematology at Geneva University Hospitals and as a Research Fellow in Dr Simonetta’s laboratory at the University of Geneva. Her research focuses on allogeneic hematopoietic stem cell transplantation, including graft-versus-host disease (GvHD), immune reconstitution, and molecular imaging of immune responses.
In November 2025, Dr Bernardi will begin a new position as “Chef de Clinique Scientifique” at Geneva University Hospitals and the University of Geneva, within Dr Simonetta’s laboratory.