Dr Géraldine Blanchard-Rohner
Dr Géraldine Blanchard-Rohner
During her PhD at the University of Oxford, Dr Blanchard-Rohner conducted several clinical trials and observational studies to better understand the kinetics of the humoral immune response following vaccination (Blanchard Rohner Blood 2008) and the role of memory B cells in the development of long-term immunity following protein polysaccharide vaccines (Blanchard Rohner Journal of Immunology 2008). She also assessed the role of maternal antibodies in the immune response to vaccination in young infants.
In parallel with her clinical training, Dr. Blanchard-Rohner conducted research projects on the vaccination of pregnant women to protect newborns against influenza and Bordetella pertussis.
During her time as “Cheffe de Clinique scientifique,” she conducted a phase II/III clinical trial assessing the immune response following a new vaccine against Bordetella pertussis using a recombinant pertussis toxin in teenagers (Blanchard Rohner, Clinical Infectious Diseases 2019).
Currently, she is the head of the Unit of Paediatric Immunology, Vaccinology, and Rheumatology in the Children’s Hospital of the HUG. She is responsible for the care of all children with immunological problems, in particular those with a primary or secondary immune defect, as well as children with autoimmune or autoinflammatory disorders. She also oversees the vaccination of children with various pathologies. Her aim is to better define the immune response to vaccination in immunosuppressed children and to further understand autoinflammatory disorders such as PFAPA syndrome.
Read more about her: https://www.hug.ch/enfants-ados/vaccinologie-pediatrique/dre-geraldine-blanchard-rohner
Immune response in immunosuppressed children (red) compared to healthy children (black).
EXPERTISE
- Vaccinology and clinical immunology.
- Primary and secondary immunodeficiency in children, auto-immune disorders and auto-inflammatory problems.
- Memory of the immune system after vaccination in adults and children with and without immune disorders.
FIVE MORe RELEVANT PUBLICATIONS
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Gold T, Gualtieri R, Posfay-Barbe K, Wildhaber BE, McLin V, Blanchard-Rohner G. Assessing vaccine-induced immunity against pneumococcus, hepatitis A and B over a 9-year follow-up in pediatric liver transplant recipients: A nationwide retrospective study. Am J Transplant. 2024 Jun;24(6):1070-1079. PMID: 38103788
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Thiriard A, Meyer B, Eberhardt CS, Loevy N, Grazioli S, Adouan W, Fontannaz P, Marechal F, L'Huillier AG, Siegrist CA, Georges D, Putignano A, Marchant A, Didierlaurent AM, Blanchard-Rohner G. Antibody response in children with multisystem inflammatory syndrome related to COVID-19 (MIS-C) compared to children with uncomplicated COVID-19. Front Immunol. 2023 Mar 15;14:1107156. PMID: 37006315
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Blanchard Rohner G, Chatzis O, Chinwangso P, Rohr M, Grillet S, Salomon C, Lemaitre B, Boonrak P, Lawpoolsri S, Clutterbuck E, Poredi IK, Wijagkanalan W, Spiegel J, Pham HT, Viviani S, Siegrist CA
Boosting Teenagers With Acellular Pertussis Vaccines Containing Recombinant or Chemically Inactivated Pertussis Toxin: A Randomized Clinical Trial. Clin Infect Dis. 2019 Mar 19;68(7):1213-1222. PMID: 30759183 -
Blanchard-Rohner G, Snape MD, Kelly DF, O'Connor D, John T, Clutterbuck EA, Ohene-Kena B, Klinger CL, Odrljin T, Pollard AJ. The B-cell response to a primary and booster course of MenACWY-CRM197_{197}197 vaccine administered at 2, 4 and 12 months of age. Vaccine. 2013 May 7;31(20):2441-8. PMID: 23566945
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Blanchard-Rohner G, Pulickal AS, Jol-van der Zijde CM, Snape MD, Pollard AJ. Appearance of peripheral blood plasma cells and memory B cells in a primary and secondary immune response in humans. Blood. 2009 Dec 3;114(24):4998-5002. PMID: 19843885