Manel Mejbri
Dr Manel Mejbri
In recent years, Dr Manel Mejbri has actively contributed to several collaborative international research studies in the field of pediatric rheumatology. She is currently involved in a retrospective study on baricitinib treatment for pediatric autoinflammatory diseases, in collaboration with Professor Brogan and Dr Papadopoulou at Great Ormond Street Hospital in London.
She also contributes to the Pediatric Rheumatology European Society (PRES) JDM Working Group, focusing on the development of clinical management guidelines for juvenile dermatomyositis with interstitial lung disease.
In 2023, Dr Mejbri completed her Medical Doctorate thesis on PSTPIP1-associated myeloid-related proteinemia inflammatory (PAMI) syndrome, a rare autoinflammatory disease. She is currently engaged in an international collaborative project reviewing treatment strategies and disease progression in this condition.
Since 2022, she has participated in the JIR-CLIPS project with the vasculitis working group, addressing global clinical practice strategies for IgA vasculitis. Additionally, she is involved in several multicenter studies on systemic-onset juvenile idiopathic arthritis and other autoinflammatory diseases, in collaboration with Professor Hofer and Dr Theodoropoulou at CHUV.
Dr Mejbri's ongoing objective is to advance clinical research and strengthen Geneva's role as a leading centre for pediatric rheumatology.
EXPERTISE
- Juvenile Idiopathic Arthritis
- Pediatric vasculitis
- Autoinflammatory disease in children
- Juvenile-onset systemic lupus erythematosus
SELECTED PUBLICATIONS
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Mejbri M, Renella R, Holzinger D, Candotti F, Hofer M, Theodoropoulou K. PSTPIP1-associated myeloid-related proteinemia inflammatory (PAMI) syndrome: A systematic review. Genes (Basel). 2023 Aug 19;14(8):1655.
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Koryllou A, Mejbri M, Theodoropoulou K, Hofer M, Carlomagno R. Chronic nonbacterial osteomyelitis in children. Children (Basel). 2021 Jun 25;8(7):551. doi:10.3390/children8070551.
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Mejbri M, Theodoropoulou K, Hofer M, Cimaz R. Interleukin-1 blockade in systemic juvenile idiopathic arthritis. Paediatr Drugs. 2020 Jun;22(3):251–62. doi:10.1007/s40272-020-00392-5.
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Bourguiba R, Deshayes S, Amaryan G, Kone-Paut I, Belot A, Sarkisyan T, Guedri R, Mejbri M, Melki I, Meinzer U, Dan D, Schleinitz N, Hentgen V, Georgin-Lavialle S. Diagnostic delays in familial Mediterranean fever: a Juvenile Inflammatory Rheumatism (JIR) cohort study. Rheumatol Int. 2024 Sep 24. doi:10.1007/s00296-024-05706-1. Epub ahead of print. PMID: 39316109.
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Baldo F, Erkens RGA, Mizuta M, Rogani G, Lucioni F, Bracaglia C, Foell D, Gattorno M, Jelusic M, Anton J, Brogan P, Canna S, Chandrakasan S, Cron RQ, De Benedetti F, Grom A, Heshin-Bekenstein M, Horne A, Khubchandani R, Ozen S, Quartier P, Ravelli A, Shimizu M, Schulert G, Scott C, Sinha R, Ruperto N, Swart JF, Vastert S, Minoia F; PReS MAS/sJIA Working Party and Paediatric Rheumatology International Trial Organization. Current treatment in macrophage activation syndrome worldwide: a systematic literature review to inform the METAPHOR project. Rheumatology (Oxford). 2025 Jan 1;64(1):32-44. doi: 10.1093/rheumatology/keae391. PMID: 39058514; PMCID: PMC11701305.
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Wallimann M., Bouayed K., E. Cannizzaro, D. Kaiser, A. Belot, E. Merlin, S. Poignant, C. Wouters, F. Hofer, T. Saurenmann, A. Koryllou, R. Carlomagno, M. Mejbri, M. Hofer, K. Theodoropoulou. Disease evolution in systemic onset juvenile idiopathic arthritis: An international, observational cohort study through JIRcohort. Pediatr Rheumatol Online J. 2023 Sep 7;21(1):96.
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Giancane G.,Campone C.,MF.Gicchino,A. Alongi,C.Bava,S.Rosina,Y.Boyko,N.Martin,Y.El Miedany,M.Harjacek,S. Hashad,M.Ioseliani,R.Burgos-Vargas,R.Joos,Ch.Scott, M.Mejbri ,Z.Morel Ayala,M.Ekelund,S. Al-Abrawi,MF.Aiche,X. N.,J.Melo-Gomes,N. Ruperto,A.Consolaro,A. Ravelli. Determinants of Discordance Between Criteria for Inactive Disease and Low Disease Activity in Juvenile Idiopathic Arthritis. Arthritis Care Res (Hoboken). 2021 Dec;73(12):1722-1729.doi: 10.1002/acr.24415.
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Vinit C, Georgin-Lavialle S, Theodoropoulou A, Barbier C, Belot A, Mejbri M, Pillet P, Pachlopnik J, Poignant S, Rebelle C, Woerner A, Koné-Paut I, Hentgen V. Real-Life Indications of Interleukin-1 Blocking Agents in Hereditary Recurrent Fevers: Data From the JIRcohort and a Literature Review. Front Immunol. 2021 Nov 11;12:744780. doi: 10.3389/fimmu.2021.744780.