Perrine Castets

Publications

 

2015

  • Guridi M, Tintignac LA, Lin S, Kupr B, Castets P, Rüegg MA. Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21. Science Signaling 2015; 8(402):ra113.

 2013

  • Castets P, Rüegg MA. MTORC1 determines autophagy through ULK1 regulation in skeletal muscle. Autophagy 2013; 9(9).
  • Ozcelik S, Fraser G, Castets P, Schaeffer V, Skachokova Z, Breu K, Clavaguera F, Sinnreich M, Kappos L, Goedert M, Tolnay M, Winkler DT. Rapamycin attenuates the progression of tau pathology in P301S tau transgenic mice. Plos One 2013; 8(5):e62459.
  • Castets P, Lin S, Rion N, Di Fulvio S, Romanino K, Guridi M, Frank S, Tintignac LA, Sinnreich M, Rüegg MA.Sustained activation of mTORC1 in skeletal muscle inhibits constitutive and starvation-induced autophagy and causes a severe, late-onset myopathy. Cell Metabolism 2013;17(5):731-744.
  • Bentzinger CF, Lin S, Romanino K, Castets P, Guridi M, Summermatter S, Handschin C, Tintignac LA, Hall MN, Rüegg MA. Differential response of skeletal muscles to mTORC1 signaling during atrophy and hypertrophy. Skeletal Muscle 2013; 3(1):6.

 2012

  • Castets P, Lescure A, Guicheney P, Allamand V. Selenoprotein N in skeletal muscle: from disease to function. Journal of Molecular Medicine 2012; 90(10).

2011

  • Rederstorff M*, Castets P*, Arbogast S, Lainé J, Vassilopoulos S, Beuvin M, Dubourg O, Vignaud A, Ferry A, Krol A, Allamand V, Guicheney P, Ferreiro A, Lescure A. Muscle increased stress-sensitivity induced by inactivation of selenoprotein N in mouse: a mammalian model for SEPN1 Related Myopathy. Plos One 2011; 6(8). *Contributed equally.
  • Castets P, Bertrand AT, Beuvin M, Ferry A, Le Grand F, Castets M, Chazot G, Rederstorff M, Krol A, Lescure A, Romero NB, Guicheney P, Allamand V. Satellite cell loss and impaired muscle regeneration in selenoprotein N deficiency. Human Molecular Genetics 2011; 20(4):694-704.
  • Lescure A, Castets P, Grunwald D, Allamand V, Howard M. Selenoprotein N: its role in disease. Chapter 22. Selenium, 3nd edition, 2011.

 2010

  • Schoenmakers E, …, Castets P, et al. A multisystem selenoprotein disorder. The Journal of Clinical Investigation 2010; 120(12):4220-4235.
  • Castets P, Bertrand AT, Beuvin M, Ferry A, Le Grand F, Castets M, Chazot G, Rederstorff M, Krol A, Lescure A, Romero NB, Guicheney P, Allamand V. Satellite cell loss is the pathomechanism leading to muscle atrophy in Selenoprotein N deficiency. Neuromuscular Disorders 2010; 20 (9):598.

2009

  • Castets P, Maugenre S, Gartioux C, Rederstorff M, Krol A, Lescure A, Tajbakhsh S, Allamand V, Guicheney P. Selenoprotein N is dynamically expressed during mouse development and detected early in muscle precursors. BMC Developmental Biology 2009; 9:46.
  • Castets P, Maugenre S, Rederstorff M, Lescure A, Krol A, Allamand V, Guicheney P. Expression of Sepn1 during murine development and regeneration. Neuromuscular Disorders 2007; 17(9):847.