Background

I hold a Bachelor’s degree in Computer Science and Applied Mathematics (1987) from the University of Geneva, Switzerland, and a Master’s degree in Computer Science (1988) from the University of Strasbourg, France. My early professional experience includes working on 2D electrophoresis gel image processing (1989) and agricultural robotics image processing (1991). I later focused on computer vision and artificial intelligence, exploring the theoretical aspects of geometrical and color features processing (1994).

In 1996, I developed two stimulation programs at the Functional Brain Mapping Laboratory (FBMLab) in Geneva, Switzerland—one for visual stimuli and another for auditory stimuli. In 1997, I initiated the development of the Cartool Software within the FBMLab, a project that remains actively maintained to this day.

Cartool features a comprehensive EEG processing pipeline, a robust microstate analysis pipeline, and a complete electrical source imaging (ESI) pipeline, along with tools for MRI processing. The software also offers highly interactive visualizations of EEG data, brain topographies, electrodes, ESI results, and MRIs, facilitating accurate and detailed scientific analysis.

Current project

The Cartool software transitioned to open source in 2024 and has been actively maintained and developed ever since. Planned future enhancements include completing the command-line interface, integrating independent component analysis (ICA) computation, improving EEG visualizations for specific clinical applications, refining ESI methods, and implementing numerous other advancements.
See: https://github.com/DenisBrunet/Cartool and https://denisbrunet.github.io/Cartool/index.html

Articles Scientifiques

Bagdasarov A, Brunet D, Michel CM, Gaffrey MS. Microstate Analysis of Continuous Infant EEG: Tutorial and Reliability. Brain Topogr. 2024 Jul;37(4):496-513. doi: 10.1007/s10548-024-01043-5. Epub 2024 Mar 2. PMID: 38430283; PMCID: PMC11199263.

Bagdasarov A, Roberts K, Brunet D, Michel CM, Gaffrey MS. Exploring the Association Between EEG Microstates During Resting-State and Error-Related Activity in Young Children. Brain Topogr. 2024 Jul;37(4):552-570. doi: 10.1007/s10548-023-01030-2. Epub 2023 Dec 23. PMID: 38141125; PMCID:
PMC11199242.

Artoni F, Maillard J, Britz J, Brunet D, Lysakowski C, Tramèr MR, Michel CM. Microsynt: Exploring the syntax of EEG microstates. Neuroimage. 2023 Aug 15;277:120196. doi: 10.1016/j.neuroimage.2023.120196. Epub 2023 Jun 5. PMID: 37286153.

Bagdasarov A, Roberts K, Brunet D, Michel CM, Gaffrey MS. Exploring the association between EEG microstates during resting-state and error-related activity in young children. Res Sq [Preprint]. 2023 May 2:rs.3.rs-2865543. doi: 10.21203/rs.3.rs-2865543/v1. Update in: Brain Topogr. 2024 Jul;37(4):552-570.
doi: 10.1007/s10548-023-01030-2. PMID: 37205415; PMCID: PMC10187414.

Bagdasarov A, Roberts K, Bréchet L, Brunet D, Michel CM, Gaffrey MS. Spatiotemporal dynamics of EEG microstates in four- to eight-year-old children: Age- and sex-related effects. Dev Cogn Neurosci. 2022 Oct;57:101134. doi: 10.1016/j.dcn.2022.101134. Epub 2022 Jul 12. PMID: 35863172; PMCID: PMC9301511.

Carboni M, Brunet D, Seeber M, Michel CM, Vulliemoz S, Vorderwülbecke BJ. Linear distributed inverse solutions for interictal EEG source localisation. Clin Neurophysiol. 2022 Jan;133:58-67. doi: 10.1016/j.clinph.2021.10.008. Epub 2021 Nov 8. PMID: 34801964.

Iannotti GR, Orepic P, Brunet D, Koenig T, Alcoba-Banqueri S, Garin DFA, Schaller K, Blanke O, Michel CM. EEG Spatiotemporal Patterns Underlying Self- other Voice Discrimination. Cereb Cortex. 2022 Apr 20;32(9):1978-1992. doi: 10.1093/cercor/bhab329. PMID: 34649280; PMCID: PMC9070353.

Damborská A, Lamoš M, Brunet D, Vulliemoz S, Bočková M, Deutschová B, Baláž M, Rektor I. Resting-State Phase-Amplitude Coupling Between the Human Subthalamic Nucleus and Cortical Activity: A Simultaneous Intracranial and Scalp EEG Study. Brain Topogr. 2021 May;34(3):272-282. doi:
10.1007/s10548-021-00822-8. Epub 2021 Jan 29. PMID: 33515171.

Bréchet L, Ziegler DA, Simon AJ, Brunet D, Gazzaley A, Michel CM. Reconfiguration of Electroencephalography Microstate Networks after Breath- Focused, Digital Meditation Training. Brain Connect. 2021 Mar;11(2):146-155. doi: 10.1089/brain.2020.0848. Epub 2021 Feb 9. PMID: 33403921; PMCID: PMC7984939.

Vorderwülbecke BJ, Carboni M, Tourbier S, Brunet D, Seeber M, Spinelli L, Seeck M, Vulliemoz S. High-density Electric Source Imaging of interictal epileptic discharges: How many electrodes and which time point? Clin Neurophysiol. 2020 Dec;131(12):2795-2803. doi: 10.1016/j.clinph.2020.09.018. Epub 2020 Oct 15. PMID: 33137569.

Bréchet L, Brunet D, Perogamvros L, Tononi G, Michel CM. EEG microstates of dreams. Sci Rep. 2020 Oct 13;10(1):17069. doi: 10.1038/s41598-020-74075-z. PMID: 33051536; PMCID: PMC7553905.

Michel CM, Brunet D. EEG Source Imaging: A Practical Review of the Analysis Steps. Front Neurol. 2019 Apr 4;10:325. doi: 10.3389/fneur.2019.00325. PMID: 31019487; PMCID: PMC6458265.

Bréchet L, Brunet D, Birot G, Gruetter R, Michel CM, Jorge J. Capturing the spatiotemporal dynamics of self-generated, task-initiated thoughts with EEG and fMRI. Neuroimage. 2019 Jul 1;194:82-92. doi: 10.1016/j.neuroimage.2019.03.029. Epub 2019 Mar 19. PMID: 30902640.

Custo A, Van De Ville D, Wells WM, Tomescu MI, Brunet D, Michel CM. Electroencephalographic Resting-State Networks: Source Localization of Microstates. Brain Connect. 2017 Dec;7(10):671-682. doi:
10.1089/brain.2016.0476. Epub 2017 Nov 17. PMID: 28938855; PMCID: PMC5736178.

Birot G, Spinelli L, Vulliémoz S, Mégevand P, Brunet D, Seeck M, Michel CM. Head model and electrical source imaging: a study of 38 epileptic patients. Neuroimage Clin. 2014 Jun 16;5:77-83. doi: 10.1016/j.nicl.2014.06.005. PMID: 25003030; PMCID: PMC4081973.

Gindrat AD, Quairiaux C, Britz J, Brunet D, Lanz F, Michel CM, Rouiller EM. Whole-scalp EEG mapping of somatosensory evoked potentials in macaque monkeys. Brain Struct Funct. 2015 Jul;220(4):2121-42. doi: 10.1007/s00429-014-0776-y. Epub 2014 May 4. PMID: 24791748; PMCID: PMC4495608.

Berchio C, Rihs TA, Michel CM, Brunet D, Apicella F, Muratori F, Gallese V, Umiltà MA. Parieto-frontal circuits during observation of hidden and visible motor acts in children. A high-density EEG source imaging study. Brain Topogr. 2014 Mar;27(2):258-70. doi: 10.1007/s10548-013-0314-x. Epub 2013 Sep 12. PMID:
24026809.

Brunet D, Murray MM, Michel CM. Spatiotemporal analysis of multichannel EEG: CARTOOL. Comput Intell Neurosci. 2011;2011:813870. doi: 10.1155/2011/813870. Epub 2011 Jan 5. PMID: 21253358; PMCID: PMC3022183.

M. M. Murray, M. De Lucia, D. Brunet, and C. M. Michel, “Principles of Topographic Analyses for Electrical Neuroimaging,” in Brain Signal Analysis: Advances in Neuroelectric and Neuromagnetic Methods, T. C. Handy, Ed. MIT Press Direct, 2009.

Murray MM, Brunet D, Michel CM. Topographic ERP analyses: a step-by-step tutorial review. Brain Topogr. 2008 Jun;20(4):249-64. doi: 10.1007/s10548-008-0054-5. Epub 2008 Mar 18. PMID: 18347966.

Khateb A, Pegna AJ, Landis T, Michel CM, Brunet D, Seghier ML, Annoni JM. Rhyme processing in the brain: an ERP mapping study. Int J Psychophysiol. 2007 Mar;63(3):240-50. doi: 10.1016/j.ijpsycho.2006.11.001. Epub 2007 Jan 10. PMID: 17222476.

Murray MM, Michel CM, Grave de Peralta R, Ortigue S, Brunet D, Gonzalez Andino S, Schnider A. Rapid discrimination of visual and multisensory memories revealed by electrical neuroimaging. Neuroimage. 2004 Jan;21(1):125-35. doi: 10.1016/j.neuroimage.2003.09.035. PMID: 14741649.

Interventions

Micro-States Workshop, Geneva, 2024: talk and workshop on Cartool
Micro-States Workshop, Bern, 2022: talk and workshop on Cartool
Lemanic Advanced EEG Course, Geneva, 2022, 2019, 2015, 2013, 2011, 2009: teaching classes and workshops
ESI Workshop, Saarbrücken, 2018: talk and workshop on Cartool
Lemanic Advanced EEG Course, Geneva, 2017: teaching classes and workshops
BaCi, Geneva, 2017: Hands-on Cartool workshop
Cartool Software Introduction, Grenoble, 2011: workshop.
Cartool Software, Geneva, 2005: teaching class and workshop.
Micro-States Workshop, Bern, 2005: talk and workshop on Cartool
Micro-States Workshop, Bern, 2001: talk and workshop on Cartool
Cartool Software, Geneva, 1998: teaching class and workshop.