A review on Gα mutations in human disease

© adapted from Figure 2 in Katanaev & Solis, 2025, EMBO Mol Med.

Mutations in the genes that encode Gα proteins are involved in many severe diseases, including cancer or encephalopathies. Advances in genetic testing have revealed a multitude of new mutations. But what causes these mutations and what impact do they have on human health? 

To find out what is known and unknown about Gα mutations in human disease, download the review from Prof. Vladimir Katanaev and Dr. Gonzalo Solis published in the journal EMBO Mol Med.

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