Analysis, Support and Training

We provide:

• Standart, Custom & Advanced Analysis
• Support of our users
• Bioinformatic training

Standard Ribo-Seq Analysis

Comprehensive analysis of ribosome profiling data for the following species: Homo sapiens, Mus musculus, Saccharomyces cerevisiae

• Quality Control: Alignment rate, mapping to coding/non-coding regions, codon periodicity
• P-site Identification: Determination of ribosome-protected fragment positions

• Quantification: Raw counts of ribosome-protected fragments per gene/transcript

Standard RNA-Seq Analysis

• Quality Control: Alignment rate, mapping to coding/non-coding regions
• Quantification: Raw counts of mRNA reads per gene/transcript

Translational Efficiency Analysis

• Differentiates between changes in mRNA abundance and alterations in translational activity
• Provides insights into translational regulation mechanisms

Custom & Advanced Analyses

• Non-standard Species: Processing and analysis of ribosome profiling data from organisms beyond the standard set
• Novel ORF Discovery: Identification of previously unannotated open reading frames
• Codon-Level Ribosome Pausing: Detection and characterization of ribosome stalling events at specific codons
• Differential Translation Analysis: Identification of genes with significant changes in translation between sample groups