Les cils cellulaires en 3D: découverte d'une gare miniature

Cilia are small hair-like organelles that extend from cells and perform many functions, including motility and signaling. Together with collaborators at the Biozentrum, University of Basel and Human Technopole in Milan, Paul Guichard and Virginie Hamel's group, has now revealed that cilia have a specialized transport hub at their base, where trains and cargos are assembled for transport throughout the cilia. Since defects in this cilia transport system can lead to e.g. cystic kidneys or blindness, the results also provide new insights into molecular basis for a variety of diseases.

The article was published in the Journal Science on July 28, 2022.

Check the Biozentrum's press release.


21 sept. 2022

News 2022