Research

FUNDAMENTAL research

  • Interoception and the regulation of emotions and behavior
  • Physiology of the insular cortex
  • Brain-body interactions and gut brain axis in psychiatric and metabolic disorders
  • Cortical glucose and metabolism sensing
  • Central control of energy balance and feeding behavior
  • Optical methods to study the brain

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 translational research

  • Role of the insular cortex and interoception in mood and anxiety disorders
  • Involvement of the insula in fronto-temporal dementia and other neurodegenerative disorders
  • Translational brain mapping across animal species
  • High-resolution human brain mapping in collaboration with the Wyss Center

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methods

Whole tissue imaging – light-sheet microscopy - 2-photon microscopy - live cell imaging - freely moving imaging – automated behavioral analysis – optogenetics – chemogenetics – neuronal circuit mapping – genetic mouse models - human tissue clearing