Research
FUNDAMENTAL research
- Interoception and the regulation of emotions and behavior
- Physiology of the insular cortex
- Brain-body interactions and gut brain axis in psychiatric and metabolic disorders
- Cortical glucose and metabolism sensing
- Central control of energy balance and feeding behavior
- Optical methods to study the brain
![PastedGraphic-1-300x233.jpg](https://www.unige.ch/medecine/Lamylab/application/files/6515/8400/5349/PastedGraphic-1-300x233.jpg)
translational research
- Role of the insular cortex and interoception in mood and anxiety disorders
- Involvement of the insula in fronto-temporal dementia and other neurodegenerative disorders
- Translational brain mapping across imaging modalities and animal species
- High-throughput human brain mapping
- Digital neuropathology and brain bank digitization
- Neuroimaging and peripheral biomarkers for psychiatric and neurodegenerative disorders
![Human_brain_Nissl.jpg](https://www.unige.ch/medecine/Lamylab/application/files/8716/1012/4779/Human_brain_Nissl.jpg)
methods
- Whole organ imaging – human tissue clearing - light-sheet microscopy - 2-photon microscopy
- High-throughput neurohistology
- Live cell imaging - freely moving imaging
- Optogenetics – chemogenetics
- Automated behavioral analysis
- Neuronal circuit mapping
- Genetic mouse models
- Transcriptomic analysis
CLINICAL RELEVANCE
- Anxiety - Depression
- Functional disorders
- Neurodegenerative diseases
- Eating disorders
- Obesity - Diabetes