Genetic medicine: functional analysis of the genome, molecular pathophysiology of monogenic and polygenic diseases such as Down syndrome, coagulation diseases and nervous system disorders (mood disorders, epilepsy).
Development: embryonic development and differentiation of mammalian cells (in mice), stem cells (embryonic cells, neurons, cancer). Functional genomics, comparative genomics, positional cloning, genotyping, bioinformatics, genomics, morphological and functional production and analysis of transgenic mice, computational analyses of genomic data, behavioural neurogenetics and brain imaging, molecular and cellular biology.
Epigenetic Control of Developmental Processes
Chromatin regulation in brain development and disease
Study of epigenetic modulations
Mechanisms involved in specifying and determining the different pancreatic cell types: cell plasticity and regeneration by cell type interconversion
Affiliated Clinical Groups
Stephan Eliez (Department of Psychiatry)
Developmental Imaging and Psychopatology Lab
Translational Research on Disorders of Hemostasis and Thrombosis
Molecular and genetic mecanism of sexual development
Ariel Ruiz i Altaba
Stemness in development and disease: Signaling, reprogramming and mechanisms of metastases
Pei-Hsuan (Xuan) WU
Function and mechanism of germline small non-coding RNAs in sperm and embryos
Computational Evolutionary Genomics