Genetic medicine: functional analysis of the genome, molecular pathophysiology of monogenic and polygenic diseases such as Down syndrome, coagulation diseases and nervous system disorders (mood disorders, epilepsy).

Development: embryonic development and differentiation of mammalian cells (in mice), stem cells (embryonic cells, neurons, cancer). Functional genomics, comparative genomics, positional cloning, genotyping, bioinformatics, genomics, morphological and functional production and analysis of transgenic mice, computational analyses of genomic data, behavioural neurogenetics and brain imaging, molecular and cellular biology.

Research Groups

Marc Abramowicz
Genomic medicine

Guillaume Andrey
Epigenetic Control of Developmental Processes

Simon Braun
Chromatin regulation in brain development and disease

Pedro Herrera
Mechanisms involved in specifying and determining the different pancreatic cell types: cell plasticity and regeneration by cell type interconversion

Marguerite Neerman-Arbez
Translational Research on Disorders of Hemostasis and Thrombosis

Affiliated Clinical Groups

Stephan Eliez (Department of Psychiatry)
Developmental Imaging and Psychopatology Lab

Serge Nef
Molecular and genetic mecanism of sexual development

Ariel Ruiz i Altaba
Stemness in development and disease: Signaling, reprogramming and mechanisms of metastases

Pei-Hsuan (Xuan) WU
Function and mechanism of germline small non-coding RNAs in sperm and embryos

Evgeny Zdobnov
Computational Evolutionary Genomics

Timothy Frayling
Common Disease Genetics and Genomics