Current Selection : 25 Research Groups

Takuji Adachi

Development of in-situ optical spectroscopy tool to investigate molecular aggregation process toward phase transition and control the resulting self-assembled structure and function (molecular crystal, supramolecular assembly, amyloid fibril etc.).

Charlotte Aumeier

Research in Marine Biology, Cell Biology and Molecular Biology

Eric Bakker

Analytical Chemistry, Electrochemistry, Electrochemical Sensors, Optical Detection Principles, Ion Optodes, Exhaustive Sensors, Photoelectric Conversion, Light Activated Extraction, Nanosphere Reagents, Materials Characterization, Polymers and Polymer Modifications, Environmental Analysis, Biomedical Analysis.

Enrica Bordignon

We study how biomolecules interact and change structures in their physiological environment using site-directed spin labeling electron paramagnetic resonance (EPR).

Thomas Bürgi

Chemistry, spectroscopy and applications of surfaces, interfaces and chiral nanomaterials: Development and application of spectroscopic techniques to probe solid-liquid interfaces, preparation and applications of chiral nanomaterials, enantiodifferentiation, vibrational optical activity, self-assembly of plasmonic nanomaterials.

Chan Cao

Nanopore sensing , single-molecule sequencing, engineering and design nanopores, rapid on-site detection

Alexandre Fürstenberg

Single-molecule fluorescence spectroscopy and super-resolution imaging: development and application of quantitative fluorescent sensors for chemical and biological systems, in particular towards understanding the dynamics of membranes and of membrane proteins such as G protein-coupled receptors.

Marcos González Gaitán

We want to understand in physical and molecular terms how cells talk to each other during development. This means our research is highly interdisciplinary: physics, cell biology, molecular biology, biochemistry, genetics... Indeed some of us in the lab are biologists, other physicists, chemists, engineers.

We are interested in the signaling events that control tissue growth: how is the shape and final size of a tissue achieved during embryogenesis?

We focus on two types of proliferation modes: growth control by morphogen gradients and asymmetric cell division in stem cells. We do this using two model systems: Drosophila and Zebrafish.

Sascha Hoogendoorn

Molecular tools to study and pertub Hedgehog signaling and the primary cilium

Gérard Hopfgartner

Analytical chemistry and mass spectrometry of low molecular weight compounds (pharmaceuticals) and macromolcules (peptides, proteins). Mass spectrometry imaging, Ionization, High resolution MS and data independent acquisition, ion mobility mass spectrometry, coupling MS with separation sciences, data analysis, MS libraries, bioanalysis, metabolism, metabolomics, lipidomics, proteomics, ultra-fast quantitative analysis.

Marko Kaksonen

We study the molecular mechanisms of membrane traffic, especially clathrin-mediated endocytosis. We aim to understand the assembly, function and regulation of the complex molecular machineries that drive the formation of endocytic vesicles. Our main experimental organism is budding yeast. We use a combination of quantitative live-cell imaging, electron microscopy, genetics, biochemistry and structural biology.

Karsten Kruse

We study the formation of spatial and temporal structures in individual biological cells and cells assemblies. The focus of our work is on theoretical descriptions of cytoskeletal dynamics. The cytoskeleton is a network of filamentous proteins, which is kept permanently out of thermodynamic equilibrium. It enables cells to divide, determines their shape and plays an important role in cell locomotion. In our descriptions, we rely heavily on concepts from non-linear dynamics and from non-equilibrium statistical mechanics.

Jérôme Lacour

Synthetic organic chemistry, chirality and molecular recognition: Organometallic reactivity and asymmetric transformations; Synthetic, physical and biological applications of highly stable (chiral) carbenium ions; NMR enantiodifferentiation of chiral substances; Hexacoordinated phosphorus chemistry

Stefan Matile

Organic Synthesis, Supramolecular Chemistry, Bioorganic Chemistry, Functional Systems, Unorthodox Interactions

Clément Mazet

Synthesis, methods development, selective catalysis, reaction mechanisms

Ross Milton

Research interests: Electrochemistry of metalloenzymes to study electron transfer and catalytic mechanisms for new biotechnologies.

Claude Piguet

Supramolecular chemistry of f-elements.
Synthesis of luminescent and magnetically active polymetallic materials. Thermodynamics of self-assembly. Molecular near-infrared to visible upconversion using linear optics. Thermotropic luminescent liquid crystals.

Amalia Poblador Bahamonde

The focus of our group is to reach an in-depth theoretical understanding of regio- and enantion-selective processes.

Michel Rickhaus

We bend, twist and shape molecules to make them proficient in self-organization. Main topics: Organic Synthesis, Supramolecular Chemistry

Aurelien Roux

My research group focuses on understanding how mechanics of lipid membranes can influence the life of cells. The enveloppe of living cells is made of lipid bilayers which impermeability and deformability ensure changes in cell shape while keeping its specific content. We are interested in understanding how membrane mechanical properties can constraint several cell processes at the molecular, cellular and multi-cellular scales. In particular, we focused on how membrane tension and rigidity influence intracellular membrane traffic (in particular endocytosis and Golgi trafficking) and cell division (in particular cytokinesis). We recently  started to be interested in multi-cellular systems, in particular epithelia, where membrane tension is proposed to play a role in cell reorganization during organ morphogenesis.

Thierry Soldati

The major aim of my group is to understand the integration of signalling, cytoskeleton and membrane trafficking in phagocytosis and its relevance to host-pathogen interactions. To this end, we use the social amoeba Dictyostelium as a model organism as it is a is genetically and biochemically tractable professional phagocyte very similar to phagocytes of the innate immune system in morphology and behaviour.

Eric Vauthey

Ultrafast photochemistry: development and applications of optical spectroscopic methods, investigations of ultrafast photoinduced molecular processes in condensed phase and at liquid interfaces. 

Jasmine Viger-Gravel

My research interests involve the development and implementation of state-of-the-art solid-state NMR methods (including hyperpolarization techniques) in combination with theoretical approaches to successfully correlate fundamental NMR interactions with their chemical activity/properties for a variety of systems ranging from nanoparticles to active pharmaceutical ingredients (APIs).

Tomasz Wesolowski

Quantum embedding theory for multi-level simulations, density functional theory, computational spectroscopy, and computational chemistry.

Nicolas Winssinger

Organic and Bio-Organic Chemistry. Direct Evolution of ligands and catalysts by programmable nucleic acid self assembly of encoded libraries. Promotion of a reaction through a bio-supramolecular interaction as a means to image an event and unleash bioactive molecules in vivo.