Doctoral program in Global Health (PhD)

Alexandra Calmy

Mme Alexandra Calmy

Professeure assistante

HUG, Département des spécialités de médecine

Alexandra Calmy obtained her medical diploma in 1994 and was trained in internal medicine
and in I in 2009 in Sydney, Australia. She was nominated Associate Professor in
2014 and is head of the HIV/AIDS Unit of the University Hospital of Geneva. Professor Calmy’s research interest focuses on public health and humanitarian response to HIV/AIDS, specifically the provision of antiretroviral therapy and management of side effects in resource limited settings. She worked with Médecins Sans Frontières in Cambodia in 1996 and has subsequently supported MSF’s HIV/AIDS work for more than 10 years. She is a member of the WHO working groups on the writing and the implementation of guidelines related to the treatment of HIV in developing countries since 2001, head of CSS6 committee at the “Agence National de Recherche surle SIDA” (ANRS), member of the scientific board of the Swiss HIV Study Cohort (SHCS), and the Federal Commission of Sexual Health in Switzerland

Main fields of interest : The research projects conducted by the HIV/AIDS team are diverse. They include Swiss and international interventional clinical trials, epidemiological studies based on data from the Swiss HIV cohort study, as well as cohort studies focusing on metabolic effects associated with HAART. The clinical trials initiated by the research team focus on 1) progression of atherosclerosis in HIV patients under HAART after 48 weeks of lipid lowering drug intervention and 2) a Swiss multicenter trial designed to assess the need for a statin prescription in patients whose antiretroviral treatment was changed. We are also interested in the early detection of bone anomalies with the use of a high resolution scanner for the analysis of the bone microstructure. Other epidemiological projects use the data of the Swiss cohort study to investigate patients with coronary heart disease, comparing their mortality with that of patients not infected with HIV. The center also participates actively in all the projects initiated by the Swiss cohort study. A cohort of patients with metabolic complications and lipodystrophy (LIPO and Metabolism Group) was established 5 years ago. This work has demonstrated that a model of integrated multidisciplinary care can be beneficial for patients with complex comorbidities. Our research group has a strong interest in clinical and epidemiological research projects conducted in countries with limited resources. Partnerships have been established with “Médecins Sans Frontières”, WHO, the Bill & Melinda Gates Foundation, and hospitals or hospital networks (Esther). These partnerships allow us to study different epidemics and patient management systems; it also offers training opportunities and a large variety of study fields.

PhD supervision and supervisors biosketches