Bioimaging Core Facility
The Bioimaging core facility is specialized in light microscopy. Its goal is to help users from experimental design & acquisitions to image processing (treatment and quantification). In addition to the maintenance of the resources of the platform and the users' training, we are also involved in the organization of workshops about ImageJ and other imaging softwares.
The facility can also help you with data presentation for oral presentation or publication (manipulation of file formats, animations, ...).
The facility is accessible to internal users (University of Geneva) but also to external users (industry & academics). For external users, please contact us at : email@example.com
❶ Microscopes & PC workstations housed in our facility are available 24/24 hours, 7/7 days for trained users, with consultation, training and support services available from 8.00 a.m. to 5.00 p.m. (Monday through Friday). Please contact directly François or Olivier.
In term of applications, our microscopes allow to study the : (i) Localization between different proteins or between diverse biological structures (co-localization, structure/ morphology, large image, 3D rendering, correlative microscopy ...); (ii) Dynamics of live cells and the movement of intracellular structures (cell tracking, multi-dimensional time-lapse acquisitions, FRAP experiments, Ca2+ imaging, photoactivation, ...); (iii) Interactions between cells or different proteins (FRET, ...).
❷ Image processing: please contact directly Nicolas or Sergei. They will be pleased to help you in your projects. Consultations and support services are available:
- Only Monday (from 9:00 a.m. to 6:00 p.m.) (for Sergei).
- From Monday to Friday (from 8:00 a.m. to 5:00 p.m.) (for Nicolas).
In term of applications, our softwares and skills in image treatment allow to quantify automatically a large diversity of images (co-localization, counting, fluorescence intensity measurements, ...).
Our bioimaging facility hosts state-of-the-art equipment with:
- 14 imaging systems (1 spinning disk confocal microscope (Nipkow), 4 confocal laser scanning microscopes (CLSM), 2 slide scanners and 7 widefield fluorescence microscopes including 1 TIRF evanescent wave microscope, 1 laser microdissector, 2 slide scanners and 1 plate scanner/ImageXpress system) that provide a wide range of applications such as cell membrane visualization, laser microdissection/isolation, colocalization analysis, F-techniques (FRAP, FRET), multi-dimensional time-lapse recordings, intravital imaging and high throughput imaging.
- 8 PC workstations for quantitative analysis and image treatments (MetaMorph, Definiens, Imaris, Huygens, NIS Nikon, ZEN Zeiss, ImageJ/ Fiji, Matlab, etc...). These PC are located just in front the main microscope ROOM C06.1742.A (ex-room 6021) in ROOM C06.1542A (ex-room 6026).
The Olympus VS120 in ROOM C06.1533.A (ex-room 6008), otherwise all other of microscopes are located in ROOM C06.1742.A (ex-room 6021).