Publications

July 2025. Polygenic prediction of body mass index and obesity through the life course and across ancestries | Nature Medicine

July 2025. Development and recalibration of a multivariable type 1 diabetes prediction model for type 1 diabetes across multiple screening studies | BMC Medicine | Full Text

July 2025. Contrasting Adult and Pediatric Populations in a Cohort of At-Risk Relatives in The T1D TrialNet Pathway to Prevention Study | Diabetes Care | American Diabetes Association

March 2025. Whole-genome sequencing analysis identifies rare, large-effect noncoding variants and regulatory regions associated with circulating protein levels - PubMed

February 2025 A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data

October 2024. Subclassification of obesity for precision prediction of cardiometabolic diseases - PubMed 

October 24. One of the first papers to use a whole genome sequencing based approach to common traits: Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height - PubMed (nih.gov) 

Aug. 24. Using clustering of genetic variants in Mendelian randomization to interrogate the causal pathways underlying multimorbidity from a common risk factor - PubMed (nih.gov)

March 24. The latest GWAS of Type 2 Diabetes: Genetic drivers of heterogeneity in type 2 diabetes pathophysiology - PubMed (nih.gov)

Feb. 24. Using genetics to further understand the causal effects of hyperglycaemia on joint diseases: Hyperglycaemia is a causal risk factor for upper limb pathologies - PubMed (nih.gov)

Feb. 24. A paper from the SOPHIA consortium, led by the Swiss Institute of Bioinformatics, and in which Tim is a workpackage lead, describes a federated database approach to obesity related research Life | Free Full-Text | A Federated Database for Obesity Research: An IMI-SOPHIA Study (mdpi.com)

Feb, 24. Liza's paper, from her PhD with the Lausanne team, is published in Nature Communications. PheWAS-based clustering of Mendelian Randomisation instruments reveals distinct mechanism-specific causal effects between obesity and educational attainment - PubMed (nih.gov)